The goal of this project is to evaluate the effectiveness of an intensive AIDS prevention program to eliminate and/or reduce risk acts that will transmit the HIV virus from 540 HIV+ youths aged 14-20 from three AIDS epicenters (Los Angeles [LA], New York [NY], and San Francisco [SF]). Changes in sexual and substance abuse risk acts will be monitored over 18 months (assessed at intake, 2, 4, 6, 12, and 18 months) as youths are randomly assigned within each site to one of the two intervention conditions designed on the AIDS Risk Reduction Model (ARRM): 1) a core module of 15-20 hours of AIDS prevention reflecting the current best intervention practice; or 2) three modules (the core module, a specialized HIV+ module, and a booster module) of 15-20 hours each, tailored specifically for HIV+ youths. There are few guidelines on how to adopt the ARRM for HIV+ youths, as the data are very limited. Therefore, prior to initiating the prevention trial, an ethnographic study will document the physical, social, and interpersonal contexts that characterize the lives of HIV+ youths and the impact of seropositivity on HIV+ youths as we observe how youths learn to adapt to their serostatus over one year. Differential effectiveness will be examined as a function of three sets of mediating factors: background characteristics (e.g., gender, sexual orientation), acquisition of the skills and norms taught in the intervention, and site. Finally, we will examine whether reductions in HIV risk acts are associated with changes in physical health and other problem behaviors (e.g., school and conduct problems, suicidality).

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Cooperative Clinical Research--Cooperative Agreements (U10)
Project #
3U10MH049059-04S1
Application #
2248627
Study Section
Special Emphasis Panel (SRCM)
Project Start
1991-09-30
Project End
1997-08-31
Budget Start
1994-09-30
Budget End
1997-08-31
Support Year
4
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of California Los Angeles
Department
Type
Other Domestic Higher Education
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Rotheram-Borus, M J; Gwadz, M; Fernandez, M I et al. (1998) Timing of HIV interventions on reductions in sexual risk among adolescents. Am J Community Psychol 26:73-96
Murphy, D A; Rotheram-Borus, M J; Reid, H M (1998) Adolescent gender differences in HIV-related sexual risk acts, social-cognitive factors and behavioral skills. J Adolesc 21:197-208
Rotheram-Borus, M J; Gillis, J R; Reid, H M et al. (1997) HIV testing, behaviors, and knowledge among adolescents at high risk. J Adolesc Health 20:216-25