The overall purpose of the University of Alabama at Birmingham's application as a NEXT site is to establish the infrastructure and expertise to aid the clinical neuroscience investigators into translating laboratory-based findings into clinical protocols.
The Specific Aims for this Core are: 1) to provide for optimal support investigators to undertake clinical research involving patients with diseases or disorders of the nervous system;2) to provide patients with neurological diseases and disorders as well as referring physicians access to clinical research treatments;and 3) to facilitate the introduction of protocols derived from the translational research of the NIH, industrial partners, or academic centers into a national cooperative consortium of neuroscience clinical centers. The NEXT site at UAB will be directed by Dr. L. Burton Nabors and Dr. Khurram Bashir, whom will provide overall leadership and administration of the NEXT site and will oversee its interactions with the Clinical Coordinating Center and Data Coordinating Center.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Cooperative Clinical Research--Cooperative Agreements (U10)
Project #
5U10NS077420-04
Application #
8709006
Study Section
Special Emphasis Panel (ZNS1)
Program Officer
Cordell, Janice
Project Start
2011-09-30
Project End
2018-06-30
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
4
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of Alabama Birmingham
Department
Neurology
Type
Schools of Medicine
DUNS #
City
Birmingham
State
AL
Country
United States
Zip Code
35294
Kolb, Stephen J; Coffey, Christopher S; Yankey, Jon W et al. (2016) Baseline results of the NeuroNEXT spinal muscular atrophy infant biomarker study. Ann Clin Transl Neurol 3:132-45
Fox, Robert J; Coffey, Christopher S; Cudkowicz, Merit E et al. (2016) Design, rationale, and baseline characteristics of the randomized double-blind phase II clinical trial of ibudilast in progressive multiple sclerosis. Contemp Clin Trials 50:166-77
Kolb, Stephen J (2013) NeuroNEXT SMA biomarkers study. Ann Neurol 74:A8