SCANR, the Stroke National Capital Area Network for Research is based in Washington, DC. SCANR is composed of 5 hospitals that already collaborate on stroke research: Washington Hospital Center, National Rehabilitation Hospital, Children's National Medical Center, Georgetown University Hospital, and Howard University Hospital. The NINDS Intramural Stroke Program is also affiliated. With the addition of George Washington University Hospital in Year 3, we will capture nearly all DC stroke patients. SCANR sites evaluated over 2100 acute strokes in 2012. Our NINDS-funded trial recruitment is excellent;we were or are in the top 5 sites for MR RESCUE, MR WITNESS, ICARE, SITT, and the IPSS. SCANR offers the Trial Network expertise in the following: acute multimodal MRI, neurorehab, pediatric stroke, and disparities. Of particular significance is our experience with recruiting urban underserved stroke patients into studies;our existing Participant Recruitment and Retention Core (PRRO Core) can be a model for other sites. We have an unusual ability to recruit a sample fully representative of our community. SCANR's scientific base includes two Carnegie Research Universities and two CTSA programs. Our preclinical expertise includes multimodal imaging, biomarkers, brain stimulation, robotics, neurorehabilitation trials, adaptive trial design, and disparities research. We are well positioned to translate early phase NINDS intramural studies into the extramural setting. We have a Phase III and two Phase II neurorehabilitation trials proposals in varying stages of development. SCANR will provide outstanding research training and mentorship for stroke clinician fellows, preparing them for productive stroke research careers. There are currently 5 directly relevant fellowship programs and two adult neurology residencies. This training joins strong multidisciplinary clinical and research expertise in stroke with much experience in research training and career development of clinician scientists.

Public Health Relevance

SCANR is located in Washington DC. As a Regional Coordinating Site, it will recruit people with stroke for trials ranging from acute intervention to rehabilitation. The unusual features of this site are that it will eventually capture nearly all stoke patients in DC, its ability to recruit urban underserved individuals, and its research strengths in multimodal MRI, neurorehabilitation, disparities, and adaptive trial design.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Cooperative Clinical Research--Cooperative Agreements (U10)
Project #
5U10NS086513-02
Application #
8739563
Study Section
Special Emphasis Panel (ZNS1-SRB-G (68))
Program Officer
Vivalda, Joanna
Project Start
2013-09-30
Project End
2018-07-31
Budget Start
2014-08-01
Budget End
2015-07-31
Support Year
2
Fiscal Year
2014
Total Cost
$381,737
Indirect Cost
$138,048
Name
Medstar Research Institute
Department
Type
DUNS #
189030067
City
Hyattsville
State
MD
Country
United States
Zip Code
20782