Abstract

Cocaine abuse is a major public health problem with enormous personal and societal costs. The need for treatments that are both effective and cost-effective is clear and compelling. The present proposal seeks to evaluate the relative effectiveness and cost-effectiveness of three, promising psychosocial treatments for cocaine abuse: (1) Supportive-Expressive psychotherapy plus drug counseling (2) Cognitive-Behavioral psychotherapy plus drug counseling, and (3) Drug Counseling alone provided by two counselors. At each of four Collaborative Treatment Sites, 90 medication-free, cocaine-dependent outpatients, of varying levels of psychiatric severity, with and without antisocial personality disorder, will be randomly assigned to one of the three treatment conditions and followed prospectively for two years. Treatment outcome will be evaluated at regular intervals, using a comprehensive and multifaceted assessment battery. Concurrently, data on law enforcement, employment, family burden, and treatment costs will be obtained. These will be combined with the treatment efficacy data and with data on outcome utilities representing a variety of perspectives. The cost-effectiveness and cost-utility of the three treatment then will be compared..

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Demonstration--Cooperative Agreements (U18)
Project #
5U18DA007663-02
Application #
2120145
Study Section
Special Emphasis Panel (SRCD (06))
Project Start
1991-09-30
Project End
1995-08-31
Budget Start
1992-09-01
Budget End
1993-08-31
Support Year
2
Fiscal Year
1992
Total Cost
Indirect Cost

  Institution

Name
Northeast Psychiatric Associates
Department
Type
DUNS #
City
Nashua
State
NH
Country
United States
Zip Code
03063

  Publications

Najavits, Lisa M; Harned, Melanie S; Gallop, Robert J et al. (2007) Six-month treatment outcomes of cocaine-dependent patients with and without PTSD in a multisite national trial. J Stud Alcohol Drugs 68:353-61
Najavits, Lisa M; Runkel, Ragna; Neuner, Christina et al. (2003) Rates and symptoms of PTSD among cocaine-dependent patients. J Stud Alcohol 64:601-6
Najavits, L M; Weiss, R D; Reif, S et al. (1998) The Addiction Severity Index as a screen for trauma and posttraumatic stress disorder. J Stud Alcohol 59:56-62
Siqueland, L; Crits-Christoph, P; Frank, A et al. (1998) Predictors of dropout from psychosocial treatment of cocaine dependence. Drug Alcohol Depend 52:1-13
Crits-Christoph, P; Siqueland, L; Chittams, J et al. (1998) Training in cognitive, supportive-expressive, and drug counseling therapies for cocaine dependence. J Consult Clin Psychol 66:484-92
Crits-Christoph, P; Siqueland, L; Blaine, J et al. (1997) The National Institute on Drug Abuse Collaborative Cocaine Treatment Study. Rationale and methods. Arch Gen Psychiatry 54:721-6