FDA Food Safety and Security Monitoring Project (U18) Grant Proposal RFA-FD-10-003 CFDA93.48Project SummaryThis grant proposal from the Ohio Department of Agriculture (ODA) is inresponse to a Funding Opportunity Announcement (FOA) for Federal assistancefrom the Food and Drug Administration (FDA) Food Emergency ResponseNetwork (FERN) as referenced above.The goal of this proposal is to develop and improve the capability of FERN torespond to chemical emergencies in food and to enhance surveillance of foodchemistry testing. The purpose of this application from the ODA ConsumerAnalytical Laboratory is to enhance the capabilities and capacities of FERNChemical Laboratories in the following instrumental areas of testing:(1) Analysis of food or food products by (a) Gas Chromatography-Mass Spectrometry (GC-MS) and (b) Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS); to screen and identify toxic substances and unknown compounds.(2) Analysis of food and food products by Inductively Coupled Plasma-Mass Spectrometry (ICP-MS) to screen and identify heavy metals and toxic elements.(3) Analysis of food or food products by Enzyme-Linked Immunosorbent Assay (ELISA) to screen and identify unknown toxins.This proposal addresses the four key areas the FDA has identified as critical andprovides detailed and in-depth information from ODA's Consumer AnalyticalLaboratory about personnel qualifications, facilities, support services, qualityassurance, management practices and security arrangements. The proposal alsodescribes progress CAL has made in providing support to the FERN ChemistryProgram to date.This grant application for the FDA Food Safety and Security Monitoring Project(U18) also provides information about the participation of ODA's ConsumerAnalytical Laboratory in various national and international Proficiency Testing(PT) programs as well as ISO-17025:2005 laboratory accreditation relatedactivities. The project narrative provides detailed information to address thecomplementary needs of the FDA and shows our thorough commitment to theFERN Chemistry Program.