IMAGING CORE - CORE C: ABSTRACT The Imaging Core (Core C) is responsible for all aspects of image acquisition and analysis.
The aims of the Imaging Core are: (1) To facilitate the acquisition of new magnetic resonance imaging (MRI) scans and new Positron Emission Tomography scans, using Pittsburgh Compound B (PiB/PET), for the BIOCARD study participants, and to analyze the newly acquired scans with state-of-the-art methodology;(2) To continue the analysis of the previously acquired MRI scans with both semi-automated and automated methods;(3) To continue to work collaboratively with the other Cores to examine combinations of biomarkers that are predictive of progression and to examine the order and pattern of biomarker change during preclinical AD, including evaluating potential new biomarkers;(4) To share the image files and related clinical information with investigators in the field, via the BIOCARD website, using the approved BIOCARD Study data sharing procedures.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Program--Cooperative Agreements (U19)
Project #
2U19AG033655-06
Application #
8740111
Study Section
Special Emphasis Panel (ZAG1-ZIJ-5 (M3))
Project Start
2014-08-15
Project End
2019-03-31
Budget Start
2014-08-15
Budget End
2015-03-31
Support Year
6
Fiscal Year
2014
Total Cost
$820,844
Indirect Cost
$267,002
Name
Johns Hopkins University
Department
Type
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218
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