ADMINISTRATIVE CORE for Influenza Immunity: Protective Mechanisms against a Pandemic Respiratory Virus. The Administrative Core of the Stanford Cooperative Center for Translational Research on Human Immunology and Biodefense will oversee the conduct of the research projects, technology development projects, pilot projects, and scientific cores proposed here. The Administrative Core will be led by Dr. Mark Davis as PI, with Drs. Ann Arvin and Harry Greenberg as co-Pis;they will anchor the Executive Committee, with the other project directors Drs. Nolan, Quake, and Butte as members. In addition, two other senior investigators from Stanford's School of Medicine will be recruited to serve on the Executive Committee on a rotating basis for two year terms.
The Specific Aims of the Adminstrative Core are to: 1) Implement administrative &leadership mechanisms that will facilitate communication and cooperation among the Stanford project leaders and with other CCHI investigators institutions to ensure a productive research effort; 2) Monitor the progress of each of the Research and Technology Development projects and their interactions with the scientific cores; 3) Provide an efficient, centralized unit for the fiscal and administrative operation of the Cooperative Center activities; 4) Develop, sponsor, and manage the Education Program. The Administrative Core personnel will be responsible for the overall organization, management, decision-making, and periodic evaluations within Stanford's CCHI. In addition, they will also oversee data sharing, protection of intellectual property in conjunction with Stanford's Office of Technology Licensing, and the involvement of institutional resources such as the GCRC.
Annual influenza epidemics are a serious public health problem;influenza pandemics are a major threat. It is important to have an efficient administrative core component to maximize use of scarce research resources which are required to develop new knowledge about the human immune response to influenza vaccines and how these responses protect against infection.
|Haynes, Winston A; Vallania, Francesco; Liu, Charles et al. (2016) EMPOWERING MULTI-COHORT GENE EXPRESSION ANALYSIS TO INCREASE REPRODUCIBILITY. Pac Symp Biocomput 22:144-153|
|Fragiadakis, Gabriela K; Baca, Quentin J; Gherardini, Pier Federico et al. (2016) Mapping the Fetomaternal Peripheral Immune System at Term Pregnancy. J Immunol 197:4482-4492|
|Sharon, Eilon; Sibener, Leah V; Battle, Alexis et al. (2016) Genetic variation in MHC proteins is associated with T cell receptor expression biases. Nat Genet 48:995-1002|
|Adams, Jarrett J; Narayanan, Samanthi; Birnbaum, Michael E et al. (2016) Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity. Nat Immunol 17:87-94|
|Rubelt, Florian; Bolen, Christopher R; McGuire, Helen M et al. (2016) Individual heritable differences result in unique cell lymphocyte receptor repertoires of naÃ¯ve and antigen-experienced cells. Nat Commun 7:11112|
|Angst, Martin S; Fragiadakis, Gabriela K; GaudilliÃ¨re, Brice et al. (2016) In Reply. Anesthesiology 124:1414-5|
|Holmes, Tyson H; He, Xiao-Song (2016) Human immunophenotyping via low-variance, low-bias, interpretive regression modeling of small, wide data sets: Application to aging and immune response to influenza vaccination. J Immunol Methods 437:1-12|
|Frei, Andreas P; Bava, Felice-Alessio; Zunder, Eli R et al. (2016) Highly multiplexed simultaneous detection of RNAs and proteins in single cells. Nat Methods 13:269-75|
|Sweeney, Timothy E; Braviak, Lindsay; Tato, Cristina M et al. (2016) Genome-wide expression for diagnosis of pulmonary tuberculosis: a multicohort analysis. Lancet Respir Med 4:213-24|
|Kovats, S; Turner, S; Simmons, A et al. (2016) West Nile virus-infected human dendritic cells fail to fully activate invariant natural killer T cells. Clin Exp Immunol 186:214-226|
Showing the most recent 10 out of 158 publications