The Pilot Projects Core will support new research initiatives during the formative stage by providing "seed" funding to small, short-term (1-2 year) pilot research projects selected through competitive review. Applications will be solicited from the general UMMS scientific community and their collaborators and will be reviewed by a panel of senior UMMS faculty investigators from the Program in Immunology and Virology. The goals of the Core will be to facilitate the entry of new investigators into the biodefense research field and improve the competitiveness of projects for external funding. Success of the program will be evaluated through review of the record of publications and success at securing external funding. The Pilot Projects program is expected to foster innovation and career development, aiding the overall objectives of the CTRHIB and the NIAID biodefense research program.

Public Health Relevance

The Pilot Projects Core helps the overall Center to foster innovation and career development by supporting small, short-term (1-2 year) pilot research projects in the early stages of development. The efforts of the Core are expected to help new investigators enter biodefense research and obtain independent external funding.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program--Cooperative Agreements (U19)
Project #
5U19AI057319-10
Application #
8452146
Study Section
Special Emphasis Panel (ZAI1-KS-I)
Project Start
Project End
Budget Start
2013-04-01
Budget End
2014-03-31
Support Year
10
Fiscal Year
2013
Total Cost
$169,112
Indirect Cost
$63,387
Name
University of Massachusetts Medical School Worcester
Department
Type
DUNS #
603847393
City
Worcester
State
MA
Country
United States
Zip Code
01655
Townsley, E; O'Connor, G; Cosgrove, C et al. (2016) Interaction of a dengue virus NS1-derived peptide with the inhibitory receptor KIR3DL1 on natural killer cells. Clin Exp Immunol 183:419-30
Woda, Marcia; Friberg, Heather; Currier, Jeffrey R et al. (2016) Dynamics of Dengue Virus (DENV)-Specific B Cells in the Response to DENV Serotype 1 Infections, Using Flow Cytometry With Labeled Virions. J Infect Dis 214:1001-9
Ramirez, Alejandro; Co, Mary; Mathew, Anuja (2016) CpG Improves Influenza Vaccine Efficacy in Young Adult but Not Aged Mice. PLoS One 11:e0150425
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Thompson, Mikayla R; Sharma, Shruti; Atianand, Maninjay et al. (2014) Interferon γ-inducible protein (IFI) 16 transcriptionally regulates type i interferons and other interferon-stimulated genes and controls the interferon response to both DNA and RNA viruses. J Biol Chem 289:23568-81
Mathew, Anuja; Townsley, Elizabeth; Ennis, Francis A (2014) Elucidating the role of T cells in protection against and pathogenesis of dengue virus infections. Future Microbiol 9:411-25
Yin, Liusong; Stern, Lawrence J (2014) A novel method to measure HLA-DM-susceptibility of peptides bound to MHC class II molecules based on peptide binding competition assay and differential IC(50) determination. J Immunol Methods 406:21-33

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