The purpose of CORE A is to provide administrative support to the Program Leaders, to the Principal Investigators of the Projects and Cores, and to the scientific personnel of the Projects and Cores of the HPSG. CORE A will be located in Dr. Chung's laboratory/office complex at the Gastrointestinal Unit of Massachusetts General Hospital. The main goals of CORE A are to manage and oversee the scientific efforts of the Projects and to coordinate scientific and administrative interactions. Thus, the specific tasks of CORE A will be to: a) facilitate interactions between Program Investigators, Scientific Advisors and administrative personnel, b) to plan and coordinate the External Scientific Advisory Group (ESAG) meeting as well as meetings between Program scientists, c) to organize and coordinate travel for scientific advisors, visiting scientists and Program Investigators, d) to assist in the organization of the seminar series and scientific symposium, e) to facilitate resource sharing including assisting in the speedy execution of material transfer agreements (MTA) and f) to assist the Program Directors and Principal Investigators in preparation of progress reports, financial reports and manuscripts for publication. CORE A will also be responsible for the resolution of any potential conflicts.

Public Health Relevance

CORE A is a crucial administrative and organizational structure that will enable the Principal Investigators and personnel of the Projects and Cores of the HPSG to focus on experimental and scientific progress.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program--Cooperative Agreements (U19)
Project #
5U19AI082630-05
Application #
8475551
Study Section
Special Emphasis Panel (ZAI1-KS-I)
Project Start
Project End
Budget Start
2013-06-01
Budget End
2014-05-31
Support Year
5
Fiscal Year
2013
Total Cost
$166,723
Indirect Cost
$44,240
Name
Massachusetts General Hospital
Department
Type
DUNS #
073130411
City
Boston
State
MA
Country
United States
Zip Code
02199
Gordon, Claire Louse; Lee, Lian Ni; Swadling, Leo et al. (2018) Induction and Maintenance of CX3CR1-Intermediate Peripheral Memory CD8+ T Cells by Persistent Viruses and Vaccines. Cell Rep 23:768-782
Duan, Xiaoqiong; Li, Shilin; Holmes, Jacinta A et al. (2018) MicroRNA 130a Regulates both Hepatitis C Virus and Hepatitis B Virus Replication through a Central Metabolic Pathway. J Virol 92:
Bengsch, Bertram; Ohtani, Takuya; Khan, Omar et al. (2018) Epigenomic-Guided Mass Cytometry Profiling Reveals Disease-Specific Features of Exhausted CD8 T Cells. Immunity 48:1029-1045.e5
Liu, Xiao; Duan, Xiaoqiong; Holmes, Jacinta A et al. (2018) A novel lncRNA regulates HCV infection through IFI6. Hepatology :
Chen, Gang; Huang, Alexander C; Zhang, Wei et al. (2018) Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response. Nature 560:382-386
Ussher, James E; Willberg, Christian B; Klenerman, Paul (2018) MAIT cells and viruses. Immunol Cell Biol 96:630-641
Bengsch, Bertram; Ohtani, Takuya; Herati, Ramin Sedaghat et al. (2018) Deep immune profiling by mass cytometry links human T and NK cell differentiation and cytotoxic molecule expression patterns. J Immunol Methods 453:3-10
Stelekati, Erietta; Chen, Zeyu; Manne, Sasikanth et al. (2018) Long-Term Persistence of Exhausted CD8 T Cells in Chronic Infection Is Regulated by MicroRNA-155. Cell Rep 23:2142-2156
Kurioka, Ayako; van Wilgenburg, Bonnie; Javan, Reza Rezaei et al. (2018) Diverse Streptococcus pneumoniae Strains Drive a Mucosal-Associated Invariant T-Cell Response Through Major Histocompatibility Complex class I-Related Molecule-Dependent and Cytokine-Driven Pathways. J Infect Dis 217:988-999
Qu, Chen; Zheng, Dandan; Li, Sai et al. (2018) Tyrosine kinase SYK is a potential therapeutic target for liver fibrosis. Hepatology :

Showing the most recent 10 out of 173 publications