The Administrative Core provides an important facilitative resource to the Center. The proposed Center involves two Research Projects, two Clinical Trial Concepts, a Pilot Project, and two Cores. The Center will have a Clinical Representative and a Research Representative to oversee the various programs. The Center will report to a Steering Committee and an External Advisory Board (EAB). Therefore, there is considerable need to coordinate the various activities and provide support. The Administrative Core A will be responsible for this coordination and support. The objectives of this core are: 1) To coordinate all Center components and ensure communication between all Investigators;2) to provide Center Investigators with help in management of budgets and personnel issues;3) to organize meetings and meeting reports;4) to oversee issues related to intellectual property and the use of human subjects;5) to assist in the actions of the Steering Committee and the External Advisory Board;6) to provide access to a data management infrastructure;and 7) to provide access to bioinformatics and biostatistics support.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program--Cooperative Agreements (U19)
Project #
5U19AI082715-05
Application #
8470124
Study Section
Special Emphasis Panel (ZAI1-QV-I)
Project Start
Project End
Budget Start
2013-05-01
Budget End
2014-04-30
Support Year
5
Fiscal Year
2013
Total Cost
$99,048
Indirect Cost
$35,556
Name
Baylor Research Institute
Department
Type
DUNS #
145745022
City
Dallas
State
TX
Country
United States
Zip Code
75204
Weng, Leiyun; Mitoma, Hiroki; Trichot, Coline et al. (2014) The E3 ubiquitin ligase tripartite motif 33 is essential for cytosolic RNA-induced NLRP3 inflammasome activation. J Immunol 193:3676-82
Rodriguez-Pla, Alicia; Patel, Pinakeen; Maecker, Holden T et al. (2014) IFN priming is necessary but not sufficient to turn on a migratory dendritic cell program in lupus monocytes. J Immunol 192:5586-98
Lu, Hongbo; Lu, Ning; Weng, Leiyun et al. (2014) DHX15 senses double-stranded RNA in myeloid dendritic cells. J Immunol 193:1364-72
Chiche, Laurent; Jourde-Chiche, NoƩmie; Whalen, Elizabeth et al. (2014) Modular transcriptional repertoire analyses of adults with systemic lupus erythematosus reveal distinct type I and type II interferon signatures. Arthritis Rheumatol 66:1583-95
Schmitt, Nathalie; Bentebibel, Salah-Eddine; Ueno, Hideki (2014) Phenotype and functions of memory Tfh cells in human blood. Trends Immunol 35:436-42
Schmitt, Nathalie; Liu, Yang; Bentebibel, Salah-Eddine et al. (2014) The cytokine TGF-? co-opts signaling via STAT3-STAT4 to promote the differentiation of human TFH cells. Nat Immunol 15:856-65
Banchereau, Romain; Cepika, Alma-Martina; Pascual, Virginia (2013) Systems approaches to human autoimmune diseases. Curr Opin Immunol 25:598-605
Bentebibel, Salah-Eddine; Lopez, Santiago; Obermoser, Gerlinde et al. (2013) Induction of ICOS+CXCR3+CXCR5+ TH cells correlates with antibody responses to influenza vaccination. Sci Transl Med 5:176ra32
Schmitt, Nathalie; Bustamante, Jacinta; Bourdery, Laure et al. (2013) IL-12 receptor ?1 deficiency alters in vivo T follicular helper cell response in humans. Blood 121:3375-85
Schmitt, Nathalie; Ueno, Hideki (2013) Human T follicular helper cells: development and subsets. Adv Exp Med Biol 785:87-94

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