The function of this Administration Core is to provide the UCACE Director with the organizational, administrative, and secretarial support to enable the scientific and clinical research goals of the program to be accomplished. The UCACE Office will be located within the ample office space allocated to the Section of Rheumatology, adjacent to the laboratories of Drs. Clark, Wilson and Weigert. Specific responsibilities of this core, embodied within the UCACE Office are as follows: 1. Coordinate the scientific activities of the program 2. Coordinate the clinical trials program 3. Oversee the documentation related to the clinical trials program 4. Facilitate interactions between investigators at the formal and informal level 5. Coordinate a standing External Scientific Advisory Committee. 6. Prepare annual progress reports 7. Organize annual formal review 8. Organize visits of other external scientists and consultants 9. Provide day to day administrative (fiscal and secretarial) support to investigators 10. Organize and administer monthly UCACE Research Seminars 11. Keep accurate records and accounts on resource utilization 12. Arrange for yearly travel of Director and Project/Core Leaders to national meetings Support services will be provided equally to all Projects and Cores.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program--Cooperative Agreements (U19)
Project #
5U19AI082724-05
Application #
8477116
Study Section
Special Emphasis Panel (ZAI1-QV-I)
Project Start
Project End
Budget Start
2013-06-01
Budget End
2014-05-31
Support Year
5
Fiscal Year
2013
Total Cost
$55,204
Indirect Cost
$19,817
Name
University of Chicago
Department
Type
DUNS #
005421136
City
Chicago
State
IL
Country
United States
Zip Code
60637
Liarski, Vladimir M; Kaverina, Natalya; Chang, Anthony et al. (2014) Cell distance mapping identifies functional T follicular helper cells in inflamed human renal tissue. Sci Transl Med 6:230ra46
Steinsbø, Øyvind; Henry Dunand, Carole J; Huang, Min et al. (2014) Restricted VH/VL usage and limited mutations in gluten-specific IgA of coeliac disease lesion plasma cells. Nat Commun 5:4041
Chang, Anthony; Ko, Kichul; Clark, Marcus R (2014) The emerging role of the inflammasome in kidney diseases. Curr Opin Nephrol Hypertens 23:204-10
Kinloch, Andrew J; Chang, Anthony; Ko, Kichul et al. (2014) Vimentin is a dominant target of in situ humoral immunity in human lupus tubulointerstitial nephritis. Arthritis Rheumatol 66:3359-70
Iversen, Rasmus; Di Niro, Roberto; Stamnaes, Jorunn et al. (2013) Transglutaminase 2-specific autoantibodies in celiac disease target clustered, N-terminal epitopes not displayed on the surface of cells. J Immunol 190:5981-91
Andrews, Sarah F; Zhang, Qingzhao; Lim, Samuel et al. (2013) Global analysis of B cell selection using an immunoglobulin light chain-mediated model of autoreactivity. J Exp Med 210:125-42
Di Niro, Roberto; Mesin, Luka; Zheng, Nai-Ying et al. (2012) High abundance of plasma cells secreting transglutaminase 2-specific IgA autoantibodies with limited somatic hypermutation in celiac disease intestinal lesions. Nat Med 18:441-5
Hsieh, Christine; Chang, Anthony; Brandt, Daniel et al. (2011) Predicting outcomes of lupus nephritis with tubulointerstitial inflammation and scarring. Arthritis Care Res (Hoboken) 63:865-74
Chang, Anthony; Henderson, Scott G; Brandt, Daniel et al. (2011) In situ B cell-mediated immune responses and tubulointerstitial inflammation in human lupus nephritis. J Immunol 186:1849-60
Kaur, Kaval; Sullivan, Meghan; Wilson, Patrick C (2011) Targeting B cell responses in universal influenza vaccine design. Trends Immunol 32:524-31

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