Abstract

The Administrative Core will provide leadership and infrastructure necessary to support all aspects of the program and will create a cohesive unit for the five projects and one additional core at four institutions in two countries. The overall objective of the Administrative core is to provide guidance, support the research projects, and promote the exchange of scientific information at all levels to ensure attainment of the Program's proposed research. In addition, the Administrative Core will ensure sound fiscal management and will establish and maintain consortium/contractual arrangements among participating institutions.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program--Cooperative Agreements (U19)
Project #
5U19AI083025-04
Application #
8378256
Study Section
Special Emphasis Panel (ZAI1-BDP-I)
Project Start
Project End
Budget Start
2012-05-01
Budget End
2013-04-30
Support Year
4
Fiscal Year
2012
Total Cost
$82,959
Indirect Cost
$15,262

  Institution

Name
University of Southern California
Department
Type
DUNS #
072933393
City
Los Angeles
State
CA
Country
United States
Zip Code
90089

  Publications

Sánchez-Aparicio, Maria T; Feinman, Leighland J; García-Sastre, Adolfo et al. (2018) Paramyxovirus V Proteins Interact with the RIG-I/TRIM25 Regulatory Complex and Inhibit RIG-I Signaling. J Virol 92:
Do?anay, Sultan; Lee, Maurice Youzong; Baum, Alina et al. (2017) Single-cell analysis of early antiviral gene expression reveals a determinant of stochastic IFNB1 expression. Integr Biol (Camb) 9:857-867
Sánchez-Aparicio, Maria Teresa; Garcin, Dominique; Rice, Charles M et al. (2017) Loss of Sendai virus C protein leads to accumulation of RIG-I immunostimulatory defective interfering RNA. J Gen Virol 98:1282-1293
Chen, Chia-Lin; Huang, Jeffrey Y; Wang, Chun-Hsiang et al. (2017) Hepatitis C virus has a genetically determined lymphotropism through co-receptor B7.2. Nat Commun 8:13882
Nelson, Emily V; Schmidt, Kristina M; Deflubé, Laure R et al. (2016) Ebola Virus Does Not Induce Stress Granule Formation during Infection and Sequesters Stress Granule Proteins within Viral Inclusions. J Virol 90:7268-7284
Pisanelli, Giuseppe; Laurent-Rolle, Maudry; Manicassamy, Balaji et al. (2016) La Piedad Michoacán Mexico Virus V protein antagonizes type I interferon response by binding STAT2 protein and preventing STATs nuclear translocation. Virus Res 213:11-22
Weber, Michaela; Sediri, Hanna; Felgenhauer, Ulrike et al. (2015) Influenza virus adaptation PB2-627K modulates nucleocapsid inhibition by the pathogen sensor RIG-I. Cell Host Microbe 17:309-319
Wang, Linya; Tian, Yongjun; Ou, Jing-hsiung James (2015) HCV induces the expression of Rubicon and UVRAG to temporally regulate the maturation of autophagosomes and viral replication. PLoS Pathog 11:e1004764
Lee, Jiyoung; Tian, Yongjun; Chan, Stephanie Tze et al. (2015) TNF-? Induced by Hepatitis C Virus via TLR7 and TLR8 in Hepatocytes Supports Interferon Signaling via an Autocrine Mechanism. PLoS Pathog 11:e1004937
Tian, Y; Kuo, C-F; Sir, D et al. (2015) Autophagy inhibits oxidative stress and tumor suppressors to exert its dual effect on hepatocarcinogenesis. Cell Death Differ 22:1025-34

Showing the most recent 10 out of 139 publications