The Administrative Core, based at the University of Maryland, Baltimore [UMB], will provide adnninistrative, financial, research oversight, and general adnninistrative support related to the EPCRTI consortium and each individual project. The Core will be co-directed by Drs. Patrik Bavoil and Jacques Ravel. The co-directors will be responsible for communicating with NIH Program Officers and organize monthly conference calls between key personnel of EPCRTI and NIH staff. The Administrative Core includes: Two Research Administrators (George Harmon, UMB Dental School, Department of Microbial Pathogenesis and Miek Segers, School of Medicine, Institute for Genome Sciences) who together will oversee all fiscal matters, resource allocation, and reporting requirements. Mr. Harmon, will also maintain an accounting system for tracking of expenses and prepares financial reports;the Office of Research Development (ORD), University of Maryland Baltimore, will handle Intellectual Property Management. ORD will act as the primary interface between UMB and technology offices at EPCRTI investigator institutions, monitors disclosures, reporting, licensing of Intellectual Property, blanket Confidentiality Disclosure Agreements and blanket Material Transfer Agreements for EPCRTI projects. The co-directors of the Administrative core will be responsible for the overall scientific leadership of the project. To guarantee success. Dr. Ravel will lead monthly meeting to discuss the technological aspect of the projects and cores (genomics and bioinformatics), while Dr. Bavoil will lead monthly group meeting on the biological aspects of the projects and core. All personnel will attend these meetings, either in persons or by teleconferences. Members of the Administrative Core and Clinical Core reside in close proximity to each other on the UMB Campus, which will facilitate daily interaction of the members.

Public Health Relevance

The Administrative Core by providing scientific and administrafive leadership will guarantee that the goals set forth by EPCRTI consortium will be accomplished in a fimely manner and that high-quality data will be rapidly availakjie to the research and clinical scientific community.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program--Cooperative Agreements (U19)
Project #
5U19AI084044-04
Application #
8380424
Study Section
Special Emphasis Panel (ZAI1-MMT-M)
Project Start
Project End
Budget Start
2012-09-01
Budget End
2013-08-31
Support Year
4
Fiscal Year
2012
Total Cost
$89,859
Indirect Cost
$19,912
Name
University of Maryland Baltimore
Department
Type
DUNS #
188435911
City
Baltimore
State
MD
Country
United States
Zip Code
21201
Ravel, Jacques; Brotman, Rebecca M (2016) Translating the vaginal microbiome: gaps and challenges. Genome Med 8:35
France, Michael T; Mendes-Soares, Helena; Forney, Larry J (2016) Genomic Comparisons of Lactobacillus crispatus and Lactobacillus iners Reveal Potential Ecological Drivers of Community Composition in the Vagina. Appl Environ Microbiol 82:7063-7073
Pittman, Kelly J; Glover, Luke C; Wang, Liuyang et al. (2016) The Legacy of Past Pandemics: Common Human Mutations That Protect against Infectious Disease. PLoS Pathog 12:e1005680
Robinson, Courtney K; Brotman, Rebecca M; Ravel, Jacques (2016) Intricacies of assessing the human microbiome in epidemiologic studies. Ann Epidemiol 26:311-21
Dareng, E O; Ma, B; Famooto, A O et al. (2016) Prevalent high-risk HPV infection and vaginal microbiota in Nigerian women. Epidemiol Infect 144:123-37
Nunn, Kenetta L; Forney, Larry J (2016) Unraveling the Dynamics of the Human Vaginal Microbiome. Yale J Biol Med 89:331-337
Neuendorf, Elizabeth; Gajer, Pawel; Bowlin, Anne K et al. (2015) Chlamydia caviae infection alters abundance but not composition of the guinea pig vaginal microbiota. Pathog Dis 73:
Wang, Liuyang; Oehlers, Stefan H; Espenschied, Scott T et al. (2015) CPAG: software for leveraging pleiotropy in GWAS to reveal similarity between human traits links plasma fatty acids and intestinal inflammation. Genome Biol 16:190
Breshears, Laura M; Edwards, Vonetta L; Ravel, Jacques et al. (2015) Lactobacillus crispatus inhibits growth of Gardnerella vaginalis and Neisseria gonorrhoeae on a porcine vaginal mucosa model. BMC Microbiol 15:276
Nunn, Kenetta L; Wang, Ying-Ying; Harit, Dimple et al. (2015) Enhanced Trapping of HIV-1 by Human Cervicovaginal Mucus Is Associated with Lactobacillus crispatus-Dominant Microbiota. MBio 6:e01084-15

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