The Administrative Core, based at the University of Maryland, Baltimore [UMB], will provide adnninistrative, financial, research oversight, and general adnninistrative support related to the EPCRTI consortium and each individual project. The Core will be co-directed by Drs. Patrik Bavoil and Jacques Ravel. The co-directors will be responsible for communicating with NIH Program Officers and organize monthly conference calls between key personnel of EPCRTI and NIH staff. The Administrative Core includes: Two Research Administrators (George Harmon, UMB Dental School, Department of Microbial Pathogenesis and Miek Segers, School of Medicine, Institute for Genome Sciences) who together will oversee all fiscal matters, resource allocation, and reporting requirements. Mr. Harmon, will also maintain an accounting system for tracking of expenses and prepares financial reports;the Office of Research Development (ORD), University of Maryland Baltimore, will handle Intellectual Property Management. ORD will act as the primary interface between UMB and technology offices at EPCRTI investigator institutions, monitors disclosures, reporting, licensing of Intellectual Property, blanket Confidentiality Disclosure Agreements and blanket Material Transfer Agreements for EPCRTI projects. The co-directors of the Administrative core will be responsible for the overall scientific leadership of the project. To guarantee success. Dr. Ravel will lead monthly meeting to discuss the technological aspect of the projects and cores (genomics and bioinformatics), while Dr. Bavoil will lead monthly group meeting on the biological aspects of the projects and core. All personnel will attend these meetings, either in persons or by teleconferences. Members of the Administrative Core and Clinical Core reside in close proximity to each other on the UMB Campus, which will facilitate daily interaction of the members.

Public Health Relevance

The Administrative Core by providing scientific and administrafive leadership will guarantee that the goals set forth by EPCRTI consortium will be accomplished in a fimely manner and that high-quality data will be rapidly availakjie to the research and clinical scientific community.

National Institute of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Research Program--Cooperative Agreements (U19)
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Special Emphasis Panel (ZAI1-MMT-M)
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University of Maryland Baltimore
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Mendes-Soares, Helena; Suzuki, Haruo; Hickey, Roxana J et al. (2014) Comparative functional genomics of Lactobacillus spp. reveals possible mechanisms for specialization of vaginal lactobacilli to their environment. J Bacteriol 196:1458-70
Bavoil, Patrik M (2014) What's in a word: the use, misuse, and abuse of the word "persistence" in Chlamydia biology. Front Cell Infect Microbiol 4:27
Bavoil, Patrik M; Byrne, Gerald I (2014) Analysis of CPAF mutants: new functions, new questions (the ins and outs of a chlamydial protease). Pathog Dis 71:287-91
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Brotman, Rebecca M; Ravel, Jacques; Bavoil, Patrik M et al. (2014) Microbiome, sex hormones, and immune responses in the reproductive tract: challenges for vaccine development against sexually transmitted infections. Vaccine 32:1543-52
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Vorimore, Fabien; Hsia, Ru-Ching; Huot-Creasy, Heather et al. (2013) Isolation of a New Chlamydia species from the Feral Sacred Ibis (Threskiornis aethiopicus): Chlamydia ibidis. PLoS One 8:e74823
Yeruva, Laxmi; Spencer, Nicole; Bowlin, Anne K et al. (2013) Chlamydial infection of the gastrointestinal tract: a reservoir for persistent infection. Pathog Dis 68:88-95
Fisher, Derek J; Fernández, Reinaldo E; Maurelli, Anthony T (2013) Chlamydia trachomatis transports NAD via the Npt1 ATP/ADP translocase. J Bacteriol 195:3381-6

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