The Statistical Core will provide the Center with highly qualified professionals witii skills in epidemiology, biostatistics, data management and computer technology. Under the leadership of Dr. Reed tiie statistical core will collaborate closely with each component of the Center in providing the resources for: efficient study design including appropriate sample size calculations and refinement of study procedures, database management, data analysis and reporting, manuscript and presentation development for study results, website development for efficient communication among projects, and training of project personnel in programming and website use as needed. The Core will be responsive and sensitive to the needs of the other components of the Center and that constitutes a truly collaborative team effort. The infrastructure for the Core already exists within the Biostatistics Research Group in tiie Division of Preventive and Behavioral Medicine which has provided design and analysis expertise, and data management resources to the Medical School for tiie past 10 years.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program--Cooperative Agreements (U19)
Project #
5U19AI084048-04
Application #
8381183
Study Section
Special Emphasis Panel (ZAI1-MMT-M)
Project Start
Project End
Budget Start
2012-09-01
Budget End
2013-08-31
Support Year
4
Fiscal Year
2012
Total Cost
$231,596
Indirect Cost
$49,942
Name
University of Massachusetts Medical School Worcester
Department
Type
DUNS #
603847393
City
Worcester
State
MA
Country
United States
Zip Code
01655
Andrade, Warrison A; Agarwal, Sarika; Mo, Shunyan et al. (2016) Type I Interferon Induction by Neisseria gonorrhoeae: Dual Requirement of Cyclic GMP-AMP Synthase and Toll-like Receptor 4. Cell Rep 15:2438-48
Shaughnessy, Jutamas; Gulati, Sunita; Agarwal, Sarika et al. (2016) A Novel Factor H-Fc Chimeric Immunotherapeutic Molecule against Neisseria gonorrhoeae. J Immunol 196:1732-40
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Su, Xiao-Hong; Wang, Bao-Xi; Le, Wen-Jing et al. (2015) Multidrug-Resistant Neisseria gonorrhoeae Isolates from Nanjing, China, Are Sensitive to Killing by a Novel DNA Gyrase Inhibitor, ETX0914 (AZD0914). Antimicrob Agents Chemother 60:621-3
Lewis, Lisa A; Ram, Sanjay (2014) Meningococcal disease and the complement system. Virulence 5:98-126
Del Tordello, Elena; Vacca, Irene; Ram, Sanjay et al. (2014) Neisseria meningitidis NalP cleaves human complement C3, facilitating degradation of C3b and survival in human serum. Proc Natl Acad Sci U S A 111:427-32
Rice, Peter A (2014) Editorial commentary: The shifting sands of gonococcal antimicrobial resistance. Clin Infect Dis 59:1092-4

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