Administrative support related to coordination of research activities between the two projects and the Scientific Core will be provided by the Administrative Core. This Core will be responsible for preparing annual research progress reports, monitoring and assisting with publications describing the Center's research, management of the Data Sharing Plan, soliciting applications for research projects to be considered for distribution of specimens from The Scientific Core, and for organizing the Annual Center Retreat and scientific review of the programs of the Center. The Administrative Core will assist in the sharing of recent findings and encourage collaborations from outside the Center. This core will also support the travel and accommodations of project and core leaders to annual HepC CRC meetings as specified in the RFA.

National Institute of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Research Program--Cooperative Agreements (U19)
Project #
Application #
Study Section
Special Emphasis Panel (ZAI1-BP-M)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Johns Hopkins University
United States
Zip Code
Bailey, Justin R; Wasilewski, Lisa N; Snider, Anna E et al. (2015) Naturally selected hepatitis C virus polymorphisms confer broad neutralizing antibody resistance. J Clin Invest 125:437-47
Chattergoon, Michael A; Latanich, Rachel; Quinn, Jeffrey et al. (2014) HIV and HCV activate the inflammasome in monocytes and macrophages via endosomal Toll-like receptors without induction of type 1 interferon. PLoS Pathog 10:e1004082
Osburn, William O; Snider, Anna E; Wells, Brittany L et al. (2014) Clearance of hepatitis C infection is associated with the early appearance of broad neutralizing antibody responses. Hepatology 59:2140-51
Grebely, Jason; Page, Kimberly; Sacks-Davis, Rachel et al. (2014) The effects of female sex, viral genotype, and IL28B genotype on spontaneous clearance of acute hepatitis C virus infection. Hepatology 59:109-20
Duggal, Priya; Thio, Chloe L; Wojcik, Genevieve L et al. (2013) Genome-wide association study of spontaneous resolution of hepatitis C virus infection: data from multiple cohorts. Ann Intern Med 158:235-45
Cox, Andrea L; Thomas, David L (2013) Hepatitis C virus vaccines among people who inject drugs. Clin Infect Dis 57 Suppl 2:S46-50
Page, Kimberly; Osburn, William; Evans, Jennifer et al. (2013) Frequent longitudinal sampling of hepatitis C virus infection in injection drug users reveals intermittently detectable viremia and reinfection. Clin Infect Dis 56:405-13
Osburn, W O; Levine, J S; Chattergoon, M A et al. (2013) Anti-inflammatory cytokines, pro-fibrogenic chemokines and persistence of acute HCV infection. J Viral Hepat 20:404-13
Liu, Lin; Fisher, Brian E; Thomas, David L et al. (2012) Spontaneous clearance of primary acute hepatitis C virus infection correlated with high initial viral RNA level and rapid HVR1 evolution. Hepatology 55:1684-91
Vickerman, Peter; Grebely, Jason; Dore, Gregory J et al. (2012) The more you look, the more you find: effects of hepatitis C virus testing interval on reinfection incidence and clearance and implications for future vaccine study design. J Infect Dis 205:1342-50

Showing the most recent 10 out of 13 publications