Abstract

This data management and stafistical core is created to sen/e the needs of each project within this malaria research center. In this core, we will establish a robust, secure, and comprehensive data management system to sen/e all projects and study sites of this center. All research personnel within this center will be familiarized with the data collecfion and processing procedures for standardization of the data format. The data management system will include security features such as double data entry, date and fime stamping of all data records with electronic signatures, audit trails to track Changes made to data and documents, quality assurance procedures, and a reporting system for summary informafion and error reports. Data generated from all projects will be maintained safely on three servers in China, Thailand and UC Irvine to provide secure and timely sharing among invesfigators of this center. A dedicated team of biostafisficians will provide biostafisfical support at each step of research design, data processing and stafisfical analyses, and assist with the wrifing of manuscripts. This team will also provide training in biostafisfics, software and GIS to participafing scientists to help bolster their biostafisfical capacity.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program--Cooperative Agreements (U19)
Project #
5U19AI089672-02
Application #
8311803
Study Section
Special Emphasis Panel (ZAI1)
Project Start
2011-07-01
Project End
2017-06-30
Budget Start
2011-07-01
Budget End
2012-06-30
Support Year
2
Fiscal Year
2011
Total Cost
$357,857
Indirect Cost

  Institution

Name
Pennsylvania State University
Department
Type
DUNS #
003403953
City
University Park
State
PA
Country
United States
Zip Code
16802

  Publications

Bunditvorapoom, Duangkamon; Kochakarn, Theerarat; Kotanan, Namfon et al. (2018) Fitness Loss under Amino Acid Starvation in Artemisinin-Resistant Plasmodium falciparum Isolates from Cambodia. Sci Rep 8:12622
Siddiqui, Faiza A; Cabrera, Mynthia; Wang, Meilian et al. (2018) Plasmodium falciparum Falcipain-2a Polymorphisms in Southeast Asia and Their Association With Artemisinin Resistance. J Infect Dis 218:434-442
Yang, Henglin; Wang, Jingyan; Liu, Hui et al. (2018) Randomized, Double-Blind, Placebo-Controlled Studies to Assess Safety and Prophylactic Efficacy of Naphthoquine-Azithromycin Combination for Malaria Prophylaxis in Southeast Asia. Antimicrob Agents Chemother 62:
Chaverra-Rodriguez, Duverney; Macias, Vanessa M; Hughes, Grant L et al. (2018) Targeted delivery of CRISPR-Cas9 ribonucleoprotein into arthropod ovaries for heritable germline gene editing. Nat Commun 9:3008
Mbenda, Huguette Gaelle Ngassa; Zeng, Weilin; Bai, Yao et al. (2018) Genetic diversity of the Plasmodium vivax phosphatidylinositol 3-kinase gene in two regions of the China-Myanmar border. Infect Genet Evol 61:45-52
Bai, Yao; Zhang, Jiaqi; Geng, Jinting et al. (2018) Longitudinal surveillance of drug resistance in Plasmodium falciparum isolates from the China-Myanmar border reveals persistent circulation of multidrug resistant parasites. Int J Parasitol Drugs Drug Resist 8:320-328
Zhao, Yan; Zeng, Jie; Zhao, Yonghong et al. (2018) Risk factors for asymptomatic malaria infections from seasonal cross-sectional surveys along the China-Myanmar border. Malar J 17:247
Deng, Zeshuai; Li, Qing; Yi, Haoan et al. (2018) Hemoglobin E protects against acute Plasmodium vivax infections in a Kachin population at the China-Myanmar border. J Infect 77:435-439
Zhong, Daibin; Koepfli, Cristian; Cui, Liwang et al. (2018) Molecular approaches to determine the multiplicity of Plasmodium infections. Malar J 17:172
Sriwichai, Patchara; Karl, Stephan; Samung, Yudthana et al. (2017) Imported Plasmodium falciparum and locally transmitted Plasmodium vivax: cross-border malaria transmission scenario in northwestern Thailand. Malar J 16:258

Showing the most recent 10 out of 115 publications