This ICEMR program endeavors to achieve a better understanding of malaria epidemiology, vector biology, and mechanisms of artemisinin resistance in Southeast Asia so that more effective, targeted malaria control can be achieved through a combination of accurate surveillance of the disease, integrated vector control, and more effective chemotherapy in this region. The involvement of a large number of key investigators from multiple institutions from the U.S., Thailand, and China, and our strategic selection of multiple study sites in China, Myanmar and Thailand require effective administration of the program. To meet this challenge, this administrative core is established to 1) provide administrative support for managing, coordinating, and supervising the research activities of this program;2) provide financial oversight of grant accounting at participating domestic and foreign institutions;and 3) provide effective administrative management of training components of this program. We have developed an administrative structure and procedures for managing and coordinating all research and training activities. This administrative core will facilitate research-related activities of the program, assist in the organization of ICEMR-related meetings, and develop and submit annual progress and financial reports. In addition to the significant dedication of the program director and codirectors in the overall administration, we have also designated in-country coordinators to further enhance daily supervision and coordination of the scientific activities at the study sites. While this core will provide overall financial administration of the program, a centralized financial administration at the endemic countries will be used to provide additional financial oversight. For the training component of this program, this core will provide administrative support for the career development projects and all other training activities within this program. The extensive collaborations and existing research and training projects among the participating institutions provide us the experience and established mechanisms for the successful administration of this program.

Public Health Relevance

This administrative core aims to provide effective administration and coordination of all scientific activities, financial oversight of grant accounting, and management of training activities of this program.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program--Cooperative Agreements (U19)
Project #
5U19AI089672-05
Application #
8691670
Study Section
Special Emphasis Panel (ZAI1-AWA-M)
Project Start
Project End
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
5
Fiscal Year
2014
Total Cost
$237,115
Indirect Cost
$251,594
Name
Pennsylvania State University
Department
Type
DUNS #
003403953
City
University Park
State
PA
Country
United States
Zip Code
16802
Wang, Meilian; Siddiqui, Faiza Amber; Fan, Qi et al. (2016) Limited genetic diversity in the PvK12 Kelch protein in Plasmodium vivax isolates from Southeast Asia. Malar J 15:537
Liu, Huaie; Feng, Guohua; Zeng, Weilin et al. (2016) A more appropriate white blood cell count for estimating malaria parasite density in Plasmodium vivax patients in northeastern Myanmar. Acta Trop 156:152-6
Zhu, Xiaotong; Zhao, Zhenjun; Feng, Yonghui et al. (2016) Genetic diversity of the Plasmodium falciparum apical membrane antigen I gene in parasite population from the China-Myanmar border area. Infect Genet Evol 39:155-62
Wang, Qinghui; Zhao, Zhenjun; Zhang, Xuexing et al. (2016) Naturally Acquired Antibody Responses to Plasmodium vivax and Plasmodium falciparum Merozoite Surface Protein 1 (MSP1) C-Terminal 19 kDa Domains in an Area of Unstable Malaria Transmission in Southeast Asia. PLoS One 11:e0151900
Wang, Xiaoming; Zhou, Guofa; Zhong, Daibin et al. (2016) Life-table studies revealed significant effects of deforestation on the development and survivorship of Anopheles minimus larvae. Parasit Vectors 9:323
Ménard, Didier; Khim, Nimol; Beghain, Johann et al. (2016) A Worldwide Map of Plasmodium falciparum K13-Propeller Polymorphisms. N Engl J Med 374:2453-64
Hu, Yue; Zhou, Guofa; Ruan, Yonghua et al. (2016) Seasonal dynamics and microgeographical spatial heterogeneity of malaria along the China-Myanmar border. Acta Trop 157:12-9
Guo, Suqin; Zhang, Wei; He, Lishan et al. (2016) Rapid evaluation of artesunate quality with a specific monoclonal antibody-based lateral flow dipstick. Anal Bioanal Chem 408:6003-8
Xu, Xin; Zhou, Guofa; Wang, Ying et al. (2016) Microgeographic Heterogeneity of Border Malaria During Elimination Phase, Yunnan Province, China, 2011-2013. Emerg Infect Dis 22:1363-70
Guo, Suqin; He, Lishan; Tisch, Daniel J et al. (2016) Pilot testing of dipsticks as point-of-care assays for rapid diagnosis of poor-quality artemisinin drugs in endemic settings. Trop Med Health 44:15

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