The Pilot Research Project Program for the University of Rochester's Center for Medical Countermeasures against Radiation (CMCR) is designed to identify and fund innovative pilot studies in radiation-related research, with an emphasis on the basic science supporting drug development to counter injuries that would result from a radiological dispersal device (RDD) or a nuclear detonation. These pilot projects are solicited from Institutions both within and outside of the CMCR Network through several approaches, including direct email solicitation and online announcement by the Radiafion Research Society (RRS) to its full membership, as well as announcement on both the UR CMCR website and the national NIH/NIAID/CMCR website. As an indication of the breadth of our announcement efforts and the diversity of applications we attract, over the course of the previous funding period the UR CMCR received a total of 74 applications from 32 institutions worldwide (including from Canada. China, France. Israel, and Japan).

Public Health Relevance

As we continue on with our Pilot program, we will build upon Its real scientific success: our current Center application is the product of mature collaborations with our Pilot awardees. Our new Center has as its anchor the continuation of the CBARMFI Lung Toxicity and Inhalation research (Jacob Finkelstein and Jacqueline Williams-Project 1), while the remaining Projects were originally nurtured by our CBARMFI Pilot Research Program 2005-2010;indeed, Drs. Kerry O'Banion and John Olschowka (Project 2-Brain), Edith Lord and Julie Ryan (Project 3-Skin and Immunology), and James Palis (Project 4-Bone Marrow) were an CBARMFI Pilot award recipients. These investigators have been sharing tissues and data, discussing experimental design, and serving as mutual scientific advisors for several years as part of their work in CBARMFI: the true nature of collaboration.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program--Cooperative Agreements (U19)
Project #
5U19AI091036-05
Application #
8705380
Study Section
Special Emphasis Panel (ZAI1)
Project Start
Project End
Budget Start
2014-08-01
Budget End
2015-07-31
Support Year
5
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of Rochester
Department
Type
DUNS #
City
Rochester
State
NY
Country
United States
Zip Code
14627
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Groves, Angela M; Johnston, Carl J; Misra, Ravi S et al. (2015) Whole-Lung Irradiation Results in Pulmonary Macrophage Alterations that are Subpopulation and Strain Specific. Radiat Res 184:639-49
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