This Core provides administrative infrastructure and budgetary oversight for the entire AADCRC. The core will support to the Project Leaders and the Principal Investigator for the submission of manuscripts and other documents pertaining to the PPG. The core will be responsible for the scheduling and coordination of meetings, conference calls, and travel for the Project Leaders to annual meetings of the AAAAI, FASEB, Keystone, or other pertinent conferences. The core will also be responsible for notifying the PI and the Project Leaders of deadlines for progress reports, and will be responsible for collecting and organizing materials from the individual projects in preparation for submission to the Institute. The core will also assist the PI and the Project Leaders in preparing the renewals of animal and human subject protocols, and will collect and retain all documentation of training of the key personnel in animal and human research in accord with institutional requirements. The core will also be responsible for budgetary oversight of the AADCRC.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program--Cooperative Agreements (U19)
Project #
1U19AI095219-01
Application #
8195754
Study Section
Special Emphasis Panel (ZAI1-PA-I (M1))
Project Start
2011-07-15
Project End
2016-06-30
Budget Start
2011-07-15
Budget End
2012-06-30
Support Year
1
Fiscal Year
2011
Total Cost
$233,966
Indirect Cost
Name
Brigham and Women's Hospital
Department
Type
DUNS #
030811269
City
Boston
State
MA
Country
United States
Zip Code
02115
Liu, Tao; Barrett, Nora A; Kanaoka, Yoshihide et al. (2018) Type 2 Cysteinyl Leukotriene Receptors Drive IL-33-Dependent Type 2 Immunopathology and Aspirin Sensitivity. J Immunol 200:915-927
Eid, Ryan C; Palumbo, Marina L; Laidlaw, Tanya M et al. (2018) A retrospective analysis of esophageal eosinophilia in patients with aspirin-exacerbated respiratory disease. J Allergy Clin Immunol Pract :
Schneider, Thomas R; Johns, Christina B; Palumbo, Marina L et al. (2018) Dietary Fatty Acid Modification for the Treatment of Aspirin-Exacerbated Respiratory Disease: A Prospective Pilot Trial. J Allergy Clin Immunol Pract 6:825-831
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Tuttle, Katherine L; Buchheit, Kathleen M; Laidlaw, Tanya M et al. (2018) A retrospective analysis of mepolizumab in subjects with aspirin-exacerbated respiratory disease. J Allergy Clin Immunol Pract 6:1045-1047
Pan, Dingxin; Buchheit, Kathleen M; Samuchiwal, Sachin K et al. (2018) COX-1 mediates IL-33-induced extracellular signal-regulated kinase activation in mast cells: Implications for aspirin sensitivity. J Allergy Clin Immunol :
Wang, H-B; Akuthota, P; Kanaoka, Y et al. (2017) Airway eosinophil migration into lymph nodes in mice depends on leukotriene C4. Allergy 72:927-936
Samuchiwal, Sachin K; Balestrieri, Barbara; Raff, Hannah et al. (2017) Endogenous prostaglandin E2 amplifies IL-33 production by macrophages through an E prostanoid (EP)2/EP4-cAMP-EPAC-dependent pathway. J Biol Chem 292:8195-8206
von Moltke, Jakob; O'Leary, Claire E; Barrett, Nora A et al. (2017) Leukotrienes provide an NFAT-dependent signal that synergizes with IL-33 to activate ILC2s. J Exp Med 214:27-37

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