The purpose of Core A is to provide administrative and project management support for the entire program and to ensure all projects and cores adhere to scientific, fiscal, and NIH reporting objectives. These functions will be crucial for the successful execution of the proposed work, given the relatively large number of cores and scientific projects participating, the extensive sharing of data and reagents envisioned amongst the different projects, and the aggressive timelines put forth from the team as whole. Although each project alone will provide important information to the field at large, extensive synergy and coordination is required to fully realize the Program's potential. Core A will specifically employ the effort of a Project Manager and a variety of Project Management functions to specifically coordinate and support each project. These will include formal program planning, monitoring, status reporting and project scheduling. In addition, a key function of Core A will be to facilitate and assist communication amongst Pis and Projects in the form of information and data exchange, preparation and submission of manuscripts, coordination/scheduling of meetings and teleconferences. In parallel, a series of activities will ensure productive communication with NIH and appointed officers including preparation and submission of NIH reports and faciltating attendance of appropriate team leaders to NIH meetings and/or conference calls. Finally the Administrative Core will oversee compliance of the overall Program and individual projects and cores with respect to fiscal and reporting obligations.

Public Health Relevance

This core will be in charge of administrative aspects of the Program. It will organize and facilitate communication amongst the various Projects participating in the Program, be responsible for monitoring progress, coordinating activities and communicating with NIAID Officers. Core A will ensure that appropriate reports are filed and that the different Projects, and the Program as a whole, adhere to the allotted budgets.

Agency
National Institute of Health (NIH)
Type
Research Program--Cooperative Agreements (U19)
Project #
5U19AI100275-03
Application #
8637927
Study Section
Special Emphasis Panel (ZAI1)
Project Start
Project End
Budget Start
Budget End
Support Year
3
Fiscal Year
2014
Total Cost
Indirect Cost
Name
La Jolla Institute
Department
Type
DUNS #
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Seumois, Grégory; Chavez, Lukas; Gerasimova, Anna et al. (2014) Epigenomic analysis of primary human T cells reveals enhancers associated with TH2 memory cell differentiation and asthma susceptibility. Nat Immunol 15:777-88
Schulten, Véronique; Peters, Bjoern; Sette, Alessandro (2014) New strategies for allergen T cell epitope identification: going beyond IgE. Int Arch Allergy Immunol 165:75-82
Arlehamn, Cecilia Lindestam; Seumois, Gregory; Gerasimova, Anna et al. (2014) Transcriptional profile of tuberculosis antigen-specific T cells reveals novel multifunctional features. J Immunol 193:2931-40
Huang, Yun; Chavez, Lukas; Chang, Xing et al. (2014) Distinct roles of the methylcytosine oxidases Tet1 and Tet2 in mouse embryonic stem cells. Proc Natl Acad Sci U S A 111:1361-6
Schulten, Véronique; Tripple, Victoria; Sidney, John et al. (2014) Association between specific timothy grass antigens and changes in TH1- and TH2-cell responses following specific immunotherapy. J Allergy Clin Immunol 134:1076-83
Gerasimova, Anna; Chavez, Lukas; Li, Bin et al. (2013) Predicting cell types and genetic variations contributing to disease by combining GWAS and epigenetic data. PLoS One 8:e54359
Vaughan, Kerrie; Peters, Bjoern; Larche, Mark et al. (2013) Strategies to query and display allergy-derived epitope data from the immune epitope database. Int Arch Allergy Immunol 160:334-45
McKinney, Denise M; Southwood, Scott; Hinz, Denise et al. (2013) A strategy to determine HLA class II restriction broadly covering the DR, DP, and DQ allelic variants most commonly expressed in the general population. Immunogenetics 65:357-70
Schulten, Veronique; Oseroff, Carla; Alam, Rafeul et al. (2013) The identification of potentially pathogenic and therapeutic epitopes from common human allergens. Ann Allergy Asthma Immunol 110:7-10