The objectives of the Administrative and Education Core (Core A) are to provide a robust infrastructure and communication network that promotes program faculty interactions and data dissemination to achieve the overall short and long-term goals of the research program. Core A is the prime decision making body for the program. Core A will: a) provide guidance and leadership on administrative and financial matters, b) facilitate communication among the research groups, cores and NIAID, c) promote scientific interactions, data sharing and discussions, d) disseminate information to the scientific community and public using the Systems Immunogenomics Webportal (SIGWP, Core E), e) host educational workshops, seminar series and web based training sessions, and f) ensure regulatory compliance and safety for all projects and cores. Success of the Cooperative Agreement is heavily dependent upon organized communication and the exchange of time-sensitive samples and complex datasets between the Research Projects and Cores. Core A is the pipeline connecting all Projects and Cores, tasked with providing the essential leadership and infrastructure that provides direction, oversight and quality control for the individual and interdependent activities of each project and core, ensuring maximum collaboration, transparent use of program resources and information exchange within our research community. This is accomplished in four broad aims: administrative and fiscal management, communication management, scientific oversight, and education outreach.
Core A is assigned the complex task of overseeing the dissemination of genetic, phenotypic, and genomics data sets between the Projects and Cores;integrating concepts across projects, enabling communication, and education outreach, which will leverage the expertise of each member of the Cooperative Agreement to expedite discovery and achievement of the research goals.
|Ferris, Martin T; Heise, Mark T (2014) Quantitative genetics in the study of virus-induced disease. Adv Virus Res 88:193-225|
|Menachery, Vineet D; Eisfeld, Amie J; Schäfer, Alexandra et al. (2014) Pathogenic influenza viruses and coronaviruses utilize similar and contrasting approaches to control interferon-stimulated gene responses. MBio 5:e01174-14|
|Schäfer, Alexandra; Baric, Ralph S; Ferris, Martin T (2014) Systems approaches to Coronavirus pathogenesis. Curr Opin Virol 6:61-9|
|Menachery, Vineet D; Yount Jr, Boyd L; Josset, Laurence et al. (2014) Attenuation and restoration of severe acute respiratory syndrome coronavirus mutant lacking 2'-o-methyltransferase activity. J Virol 88:4251-64|
|Menachery, Vineet D; Debbink, Kari; Baric, Ralph S (2014) Coronavirus non-structural protein 16: evasion, attenuation, and possible treatments. Virus Res 194:191-9|
|Rasmussen, Angela L; Okumura, Atsushi; Ferris, Martin T et al. (2014) Host genetic diversity enables Ebola hemorrhagic fever pathogenesis and resistance. Science 346:987-91|
|Gibbs, David L; Gralinski, Lisa; Baric, Ralph S et al. (2014) Multi-omic network signatures of disease. Front Genet 4:309|
|Josset, Laurence; Tchitchek, Nicolas; Gralinski, Lisa E et al. (2014) Annotation of long non-coding RNAs expressed in collaborative cross founder mice in response to respiratory virus infection reveals a new class of interferon-stimulated transcripts. RNA Biol 11:875-90|
|Scobey, Trevor; Yount, Boyd L; Sims, Amy C et al. (2013) Reverse genetics with a full-length infectious cDNA of the Middle East respiratory syndrome coronavirus. Proc Natl Acad Sci U S A 110:16157-62|
|Chen, Yaoqing; Rajashankar, Kanagalaghatta R; Yang, Yang et al. (2013) Crystal structure of the receptor-binding domain from newly emerged Middle East respiratory syndrome coronavirus. J Virol 87:10777-83|
Showing the most recent 10 out of 14 publications