The administrative core will provide a management plan to coordinate the whole FLUOMICS consortium by 1) the establishment of an organizational structure centered around an Executive Committee responsible for monitoring overall program progress, implementing a Pilot Research Program, and making decisions on staffing plans, allocation of resources, scientific core usage and other policies;2) the coordination of conference calls and of annual meetings between the Pis, selected key personnel, the Steering Committee and NIAID;3) assisting the members of this consortium in reagents and data sharing, manuscript preparations, public release of data and submission of annual progress reports to the NIH;and 4) providing training opportunities in Systems Biology for the infection disease scientist. The Core Director has expertise in the coordination of program projects and big consortiums, as he is the Director of one of the NIAID Centers of Excellence of Influenza Research and Surveillance. This FLUOMICS proposal complements and does not overlap with the Center of Excellence, as the influenza center does not include the use of a systems biology approach in its research agenda. The Core Co-Director is in charge ofthe training program to be implemented in years 2 to 5 and he has past experience in organizing training for students in systems biology approaches.

Public Health Relevance

We are planning to create an innovative discovery platform integrating global scale OMICS and systems biology approaches to identify novel host genes and immune networks that impact susceptibility to influenza virus infection. This will be done through an intercollaborative multidisciplinary approach involving 3 scientific projects, 3 -OMICS cores, a Modeling Core, a Virus Core, a Data Management and Resources Dissemination Core and 8 different institutions. The administrative will take care of coordinating such a complex organization to assure maximal research progress, and organize a training symposia in systems biology.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program--Cooperative Agreements (U19)
Project #
1U19AI106754-01
Application #
8580816
Study Section
Special Emphasis Panel (ZAI1-EC-M (M1))
Project Start
Project End
Budget Start
2013-06-26
Budget End
2014-05-31
Support Year
1
Fiscal Year
2013
Total Cost
$106,820
Indirect Cost
$17,652
Name
Icahn School of Medicine at Mount Sinai
Department
Type
DUNS #
078861598
City
New York
State
NY
Country
United States
Zip Code
10029
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