The goal ofthe Metabolomics Core (Core D) is to provide a central resource that will facilitate high throughput characterization ofthe metabolome in influenza virus infected cells and fissues. We will validate relevant metabolites and localize metabolites within infected fissues samples. The core will also design strategies to uncover host metabolic pathways that are impacted by, and that influence influenza virus infecfion and disease pathogenesis.

Public Health Relevance

An better understanding of influenza infecfion and pathogenesis requires state-of-the-art tools for measuring the metabolism of infected cells. This Core will perform analysis of small metabolites associated with virus infecfion. These studies will help to define the fundamental ways that influenza causes disease

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program--Cooperative Agreements (U19)
Project #
1U19AI106754-01
Application #
8580821
Study Section
Special Emphasis Panel (ZAI1-EC-M (M1))
Project Start
Project End
Budget Start
2013-06-26
Budget End
2014-05-31
Support Year
1
Fiscal Year
2013
Total Cost
$340,673
Indirect Cost
$56,296
Name
Icahn School of Medicine at Mount Sinai
Department
Type
DUNS #
078861598
City
New York
State
NY
Country
United States
Zip Code
10029
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