Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program--Cooperative Agreements (U19)
Project #
1U19AI106761-01
Application #
8577277
Study Section
Special Emphasis Panel (ZAI1-EC-M (M1))
Project Start
2013-06-21
Project End
2018-05-31
Budget Start
2013-06-21
Budget End
2014-05-31
Support Year
1
Fiscal Year
2013
Total Cost
$813,839
Indirect Cost
$309,337
Name
Seattle Biomedical Research Institute
Department
Type
DUNS #
070967955
City
Seattle
State
WA
Country
United States
Zip Code
98109
Peterson, Eliza J R; Ma, Shuyi; Sherman, David R et al. (2016) Network analysis identifies Rv0324 and Rv0880 as regulators of bedaquiline tolerance in Mycobacterium tuberculosis. Nat Microbiol 1:16078
Rothchild, Alissa C; Sissons, James R; Shafiani, Shahin et al. (2016) MiR-155-regulated molecular network orchestrates cell fate in the innate and adaptive immune response to Mycobacterium tuberculosis. Proc Natl Acad Sci U S A 113:E6172-E6181
Turkarslan, Serdar; Peterson, Eliza J R; Rustad, Tige R et al. (2015) A comprehensive map of genome-wide gene regulation in Mycobacterium tuberculosis. Sci Data 2:150010
Moguche, Albanus O; Shafiani, Shahin; Clemons, Corey et al. (2015) ICOS and Bcl6-dependent pathways maintain a CD4 T cell population with memory-like properties during tuberculosis. J Exp Med 212:715-28
Ma, Shuyi; Minch, Kyle J; Rustad, Tige R et al. (2015) Integrated Modeling of Gene Regulatory and Metabolic Networks in Mycobacterium tuberculosis. PLoS Comput Biol 11:e1004543
Andersen, Peter; Urdahl, Kevin B (2015) TB vaccines; promoting rapid and durable protection in the lung. Curr Opin Immunol 35:55-62
Minch, Kyle J; Rustad, Tige R; Peterson, Eliza J R et al. (2015) The DNA-binding network of Mycobacterium tuberculosis. Nat Commun 6:5829
Di Paolo, Nelson C; Shafiani, Shahin; Day, Tracey et al. (2015) Interdependence between Interleukin-1 and Tumor Necrosis Factor Regulates TNF-Dependent Control of Mycobacterium tuberculosis Infection. Immunity 43:1125-36
Zak, Daniel E; Aderem, Alan (2015) Systems integration of innate and adaptive immunity. Vaccine 33:5241-8
Urdahl, Kevin B (2014) Understanding and overcoming the barriers to T cell-mediated immunity against tuberculosis. Semin Immunol 26:578-87

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