The goal of Core C - Data Management and Resources Dissemination (DMRD) is to provide a centralized repository for the various systems biology datasets, programmatic tools and results generated by the "Modeling Host Responses to Understand Severe Human Virus Infections" project, and to make this repository easily accessible to the members of the research team as well as the wider scientific community. The DMRD will be responsible for providing IT hardware and software support to establish and maintain a centralized database integrated with a Laboratory Information Management System, that will be used to track complex experimental flows, exchange data and information between the experimentalists and computational scientists, and facilitate collaboration between the various team members of this multidisplinary and multi-Pl research effort. To enable the wider scientific community to benefit from the research of this project, this core will coordinate with other components of the project to rapidly deposit data to public repositories and setup a dedicated web-portal that will provide information about the major milestones of the project to enable the wider systems biology and virology community to have unified access to the resources generated by this project.

Public Health Relevance

Systematic data integration of the rich OMICs datasets collected by the various components of this project to gain a systems level understanding human host response to pathogenic viruses, requires a dependable and flexible data management system. In addition, rapid and efficient sharing of information between team members and the general community are essential for the broader impact of this project.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program--Cooperative Agreements (U19)
Project #
5U19AI106772-02
Application #
8667406
Study Section
Special Emphasis Panel (ZAI1-EC-M)
Project Start
Project End
Budget Start
2014-06-01
Budget End
2015-05-31
Support Year
2
Fiscal Year
2014
Total Cost
$174,691
Indirect Cost
$58,617
Name
University of Wisconsin Madison
Department
Type
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715
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Menachery, Vineet D; Eisfeld, Amie J; Schäfer, Alexandra et al. (2014) Pathogenic influenza viruses and coronaviruses utilize similar and contrasting approaches to control interferon-stimulated gene responses. MBio 5:e01174-14
Diamond, Michael S; Schoggins, John W (2013) Host restriction factor screening: let the virus do the work. Cell Host Microbe 14:229-31