The Administrative Core of the JCVI Genomic Center for Infectious Diseases Program will act in the overall management, coordination, and supervision of the entire Program. The Administrative core will be led by Dr. Nierman as Principal Investigator and Dr. Nelson as Co-PI, both of whom have extensive experience in managing large programs and contracts. Supporting the Drs. Nieman and Nelson, the Administrative Core will have a dedicated Project Manager. With Dr. Nierman's and Nelson's expertise, the administrative core will oversee and ensure the scientific progress of the Program and its administrative and fiscal integrity through eight specific aims:
Aim 1. Develop and implement a Center Management Plan.
Aim 2. Establish the Center Research Projects.
Aim 3. Initiate and maintain communicates with the other Centers and with the NIAID staff.
Aim 4. Assure the rapid dissemination of data and other resources.
Aim 5. Monitor Center progress including timelines and milestones.
Aim 6. Implement Training Program, Supplemental Research Projects, and outreach activities.
Aim 7. Provide for Center participation in Annual Programmatic Meeting, site visits, teleconference calls, and with the Steering Committee.
Aim 8. Establish an Intellectual Property Plan. The central theme of the JCVI GCID is the application of innovative genomics-based approaches to study pathogens and determinants of their virulence, drug-resistance, immune evasion, and interactions with the host and host microbiome. The Administrative Core will support all four Research Projects. All the Projects and the Administrative Core activities are congruent with the central theme.
|Shao, Lulu; Fischer, David D; Kandasamy, Sukumar et al. (2016) Comparative In Vitro and In Vivo Studies of Porcine Rotavirus G9P and Human Rotavirus Wa G1P. J Virol 90:142-51|
|Rojas, Laura J; Wright, Meredith S; De La Cadena, Elsa et al. (2016) Initial Assessment of the Molecular Epidemiology of blaNDM-1 in Colombia. Antimicrob Agents Chemother 60:4346-50|
|Chavda, Kalyan D; Chen, Liang; Fouts, Derrick E et al. (2016) Comprehensive Genome Analysis of Carbapenemase-Producing Enterobacter spp.: New Insights into Phylogeny, Population Structure, and Resistance Mechanisms. MBio 7:|
|Rosas-Salazar, Christian; Shilts, Meghan H; Tovchigrechko, Andrey et al. (2016) Differences in the Nasopharyngeal Microbiome During Acute Respiratory Tract Infection With Human Rhinovirus and Respiratory Syncytial Virus in Infancy. J Infect Dis 214:1924-1928|
|Nelson, Martha I; Stucker, Karla M; Schobel, Seth A et al. (2016) Introduction, Evolution, and Dissemination of Influenza A Viruses in Exhibition Swine in the United States during 2009 to 2013. J Virol 90:10963-10971|
|Schobel, Seth A; Stucker, Karla M; Moore, Martin L et al. (2016) Respiratory Syncytial Virus whole-genome sequencing identifies convergent evolution of sequence duplication in the C-terminus of the G gene. Sci Rep 6:26311|
|Shilts, Meghan H; Rosas-Salazar, Christian; Tovchigrechko, Andrey et al. (2016) Minimally Invasive Sampling Method Identifies Differences in Taxonomic Richness of Nasal Microbiomes in Young Infants Associated with Mode of Delivery. Microb Ecol 71:233-42|
|Chen, Rubing; Puri, Vinita; Fedorova, Nadia et al. (2016) Comprehensive Genome Scale Phylogenetic Study Provides New Insights on the Global Expansion of Chikungunya Virus. J Virol 90:10600-10611|
|Rosas-Salazar, Christian; Shilts, Meghan H; Tovchigrechko, Andrey et al. (2016) Nasopharyngeal Microbiome in Respiratory Syncytial Virus Resembles Profile Associated with Increased Childhood Asthma Risk. Am J Respir Crit Care Med 193:1180-3|
|Nelson, Martha I; Wentworth, David E; Das, Suman R et al. (2016) Evolutionary Dynamics of Influenza A Viruses in US Exhibition Swine. J Infect Dis 213:173-82|
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