Abstract

Public Health Relevance

This project will take advantage of the high endemicity of leptospirosis in Sri Lanka and a high diversity of Leptospira present in the environment in this country that are transmitted to humans, towards making better diagnostic tests for leptospirosis. These improved tests for leptospirosis will be useful in Sri Lanka and elsewhere because of the generalizability of the approach, and will allow for accurate estimations in the future for Global Burden of Disease studies for leptospirosis.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program--Cooperative Agreements (U19)
Project #
1U19AI115658-01
Application #
8820059
Study Section
Special Emphasis Panel (ZAI1-AWA-M (S2))
Project Start
Project End
Budget Start
2015-09-01
Budget End
2016-02-29
Support Year
1
Fiscal Year
2015
Total Cost
$46,657
Indirect Cost
$8,337

  Institution

Name
University of California San Diego
Department
Type
DUNS #
804355790
City
La Jolla
State
CA
Country
United States
Zip Code
92093

  Publications

Agampodi, Suneth B; Dahanayaka, Niroshan J; Nöckler, Karsten et al. (2016) Redefining Gold Standard Testing for Diagnosing Leptospirosis: Further Evidence from a Well-Characterized, Flood-Related Outbreak in Sri Lanka. Am J Trop Med Hyg 95:531-6
Fouts, Derrick E; Matthias, Michael A; Adhikarla, Haritha et al. (2016) What Makes a Bacterial Species Pathogenic?:Comparative Genomic Analysis of the Genus Leptospira. PLoS Negl Trop Dis 10:e0004403