This application proposes "The National Dental PBRN (NDPBRN)", a national collaborative of practices and organizations across the United States that will engage practitioners in the excitement of discovery for the benefit of everyday clinical practice and its patients. Consistent with specifications in the RFA itself, the Specific Aims will be to: (1) support the infrastructure and conduct of national oral health research studies in dental practices on topics of importance to practitioners;(2) provide evidence useful in daily patient care;(3) facilitate the translation of research findings into clinical practice. NDPBRN also will aim to broaden the scope of dental practice via certain studies to better integrate dental practice into the larger health care system, and to reach out further to dental education to inculcate in graduating clinicians an appreciation for the role of science in everyday clinical practice. NDPBRN will measure and document this change and the network's impact on bringing about change in everyday clinical practice. NDPBRN will accomplish these aims by building upon the many lessons learned from its exceptionally productive current national network, and include additional states and activities. We are fortunate to have gained important experience these past six years using the same regional funding structure and administrative structure mandated in the RFA. The effectiveness of this structure is evident from our current network's high level of productivity, as judged by number of publications and completed studies, the size, scope, quality (e.g. Good Clinical Practice audit trail standards), and diversity of studies, and impact on health and daily clinical practice. NDPBRN will comprise six regions, a Data Coordinating Core (mainly at Westat, Inc.), and an Administrative Core largely based at the University of Alabama at Birmingham (UAB). Other key elements of the governing and administrative structure will include a Practitioner Steering Committee, Regional Directors Committee, Director of Dental Informatics, Director of Communications &Dissemination, Director of Practitioner Training &Education Component, Director of Academic Collaborations, Protocol Consultants Group, Patient Advisory Board, Publications &Presentations Committee, Central IRB, Data &Safety Monitoring Board, and NIDCR staff. The Western region will be led by Kaiser Permanente, the Midwest region by Health Partners Research Foundation, the Southwest region by the Univ. of Texas Health Science Center at San Antonio, the South Central region by UAB, the South Atlantic region by the Univ. of Florida, and the Northeast region by the Univ. of Rochester.

Public Health Relevance

The network's overall goal will be to do science that is immediately applicable to everyday clinical practice, to foster its movement into everyday clinical practice, and thereby help improve the health of the nation. NDPBRN will continue to comprise a highly collaborative environment wherein clinicians in everyday clinical practice, academic researchers, patient representatives, and their communities become engaged in win-win activities that each group sees as mutually beneficial.

National Institute of Health (NIH)
National Institute of Dental & Craniofacial Research (NIDCR)
Research Program--Cooperative Agreements (U19)
Project #
Application #
Study Section
Special Emphasis Panel (ZDE1-JH (23))
Program Officer
Denucci, D J
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Alabama Birmingham
Schools of Dentistry
United States
Zip Code
Kakudate, Naoki; Sumida, Futoshi; Matsumoto, Yuki et al. (2015) Dentists' decisions to conduct caries risk assessment in a Dental Practice-Based Research Network. Community Dent Oral Epidemiol 43:128-34
Gordan, Valeria V; National Dental PBRN Collaborative Group (2014) Translating research into everyday clinical practice: lessons learned from a USA national dental practice-based research network. Tex Dent J 131:590-9
Fellows, Jeffrey L; Gordan, Valeria V; Gilbert, Gregg H et al. (2014) Dentist and practice characteristics associated with restorative treatment of enamel caries in permanent teeth: multiple-regression modeling of observational clinical data from the National Dental PBRN. Am J Dent 27:91-9
Ray, Midge N; Funkhouser, Ellen; Williams, Jessica H et al. (2014) Smoking-cessation e-referrals: a national dental practice-based research network randomized controlled trial. Am J Prev Med 46:158-65
Norton, Wynne E; Funkhouser, Ellen; Makhija, Sonia K et al. (2014) Concordance between clinical practice and published evidence: findings from The National Dental Practice-Based Research Network. J Am Dent Assoc 145:22-31
Riley 3rd, Joseph L; Gordan, Valeria V; Hudak-Boss, Susan E et al. (2014) Concordance between patient satisfaction and the dentist's view: findings from The National Dental Practice-Based Research Network. J Am Dent Assoc 145:355-62
Makhija, Sonia K; Gilbert, Gregg H; Funkhouser, Ellen et al. (2014) Twenty-month follow-up of occlusal caries lesions deemed questionable at baseline: findings from the National Dental Practice-Based Research Network. J Am Dent Assoc 145:1112-8
Makhija, S K; Gilbert, G H; Funkhouser, E et al. (2014) Characteristics, detection methods and treatment of questionable occlusal carious lesions: findings from the national dental practice-based research network. Caries Res 48:200-7
Gordan, Valeria V; Riley 3rd, Joseph; Geraldeli, Saulo et al. (2014) The decision to repair or replace a defective restoration is affected by who placed the original restoration: findings from the National Dental PBRN. J Dent 42:1528-34
Law, Alan S; Nixdorf, Donald R; Rabinowitz, Ira et al. (2014) Root canal therapy reduces multiple dimensions of pain: a national dental practice-based research network study. J Endod 40:1738-45

Showing the most recent 10 out of 28 publications