The Administrative Core ofthe proposed U19 Center will be responsible for centralized management of the scientific, organizational, financial, contractual, and communication requirements ofthe Center, including handling meeting coordination and ensuring dissemination of information across and between Center projects. The Administrative Core oversight of the Center's projects and Cores will ensure that Center activities synergize and that discoveries are coherently and systematically communicated to scientists within the Center, to the Consortium members, and to the public through presentation at local, national, and international conferences. Dr. Timothy Fennell will serve as Center Director and will have overall responsibility for the Center's administration, including coordinating meetings and symposia, coordinating reports and manuscripts, and monitoring project timelines and budgets. Center support will be provided by the existing RTI International (RTI) infrastructure (i.e., contracts, finance, and facilities). Dr. Fennell will be assisted by Dr. Kenneth Rehder, who reports directly to Dr. Jennie Hunter-Cevera, RTI's Executive Vice President (EVP) for Corporate Development and EVP of Discovery and Analytical Sciences.

National Institute of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
Research Program--Cooperative Agreements (U19)
Project #
Application #
Study Section
Special Emphasis Panel (ZES1-SET-V)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Research Triangle Institute
Research Triangle
United States
Zip Code
Aldossari, Abdullah A; Shannahan, Jonathan H; Podila, Ramakrishna et al. (2015) Influence of physicochemical properties of silver nanoparticles on mast cell activation and degranulation. Toxicol In Vitro 29:195-203
Poitras, Eric P; Levine, Michael A; Harrington, James M et al. (2015) Development of an analytical method for assessment of silver nanoparticle content in biological matrices by inductively coupled plasma mass spectrometry. Biol Trace Elem Res 163:184-92
Thompson, Leslie C; Urankar, Rakhee N; Holland, Nathan A et al. (2014) C?? exposure augments cardiac ischemia/reperfusion injury and coronary artery contraction in Sprague Dawley rats. Toxicol Sci 138:365-78
Vidanapathirana, Achini K; Thompson, Leslie C; Mann, Erin E et al. (2014) PVP formulated fullerene (C60) increases Rho-kinase dependent vascular tissue contractility in pregnant Sprague Dawley rats. Reprod Toxicol 49:86-100
Smith, Matthew J; Brown, Jared M; Zamboni, William C et al. (2014) From immunotoxicity to nanotherapy: the effects of nanomaterials on the immune system. Toxicol Sci 138:249-55
Thompson, Leslie C; Frasier, Chad R; Sloan, Ruben C et al. (2014) Pulmonary instillation of multi-walled carbon nanotubes promotes coronary vasoconstriction and exacerbates injury in isolated hearts. Nanotoxicology 8:38-49
Shannahan, Jonathan H; Lai, Xianyin; Ke, Pu Chun et al. (2013) Silver nanoparticle protein corona composition in cell culture media. PLoS One 8:e74001