The Biostatistics Core will provide comprehensive statistical support to the PMT projects: In particular,' this core will assist with the design and analysis of functional genomics, computational genomics, and clinical studies, as highlighted in the following specific aims.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Program--Cooperative Agreements (U19)
Project #
5U19GM061390-13
Application #
8377560
Study Section
Special Emphasis Panel (ZRG1-GGG-M)
Project Start
Project End
Budget Start
2012-07-01
Budget End
2013-06-30
Support Year
13
Fiscal Year
2012
Total Cost
$121,864
Indirect Cost
$39,464
Name
University of California San Francisco
Department
Type
DUNS #
094878337
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Yee, S W; Giacomini, M M; Hsueh, C-H et al. (2016) Metabolomic and Genome-wide Association Studies Reveal Potential Endogenous Biomarkers for OATP1B1. Clin Pharmacol Ther 100:524-536
Zhou, Kaixin; Yee, Sook Wah; Seiser, Eric L et al. (2016) Variation in the glucose transporter gene SLC2A2 is associated with glycemic response to metformin. Nat Genet 48:1055-9
Zheng, Yi; Chen, Xijing; Benet, Leslie Z (2016) Reliability of In Vitro and In Vivo Methods for Predicting the Effect of P-Glycoprotein on the Delivery of Antidepressants to the Brain. Clin Pharmacokinet 55:143-67
Benet, Leslie Z; Hosey, Chelsea M; Ursu, Oleg et al. (2016) BDDCS, the Rule of 5 and drugability. Adv Drug Deliv Rev 101:89-98
Rotroff, Daniel M; Oki, Noffisat O; Liang, Xiaomin et al. (2016) Pharmacometabolomic Assessment of Metformin in Non-diabetic, African Americans. Front Pharmacol 7:135
Yee, S W; Momozawa, Y; Kamatani, Y et al. (2016) Genomewide Association Studies in Pharmacogenomics: Meeting Report of the NIH Pharmacogenomics Research Network-RIKEN (PGRN-RIKEN) Collaboration. Clin Pharmacol Ther 100:423-426
Li, M; Seiser, E L; Baldwin, R M et al. (2016) ABC transporter polymorphisms are associated with irinotecan pharmacokinetics and neutropenia. Pharmacogenomics J :
Eclov, Rachel J; Kim, Mee J; Smith, Robin P et al. (2016) In Vivo Hepatic Enhancer Elements in the Human ABCG2 Locus. Drug Metab Dispos :
Hibma, Jennifer E; Zur, Arik A; Castro, Richard A et al. (2016) The Effect of Famotidine, a MATE1-Selective Inhibitor, on the Pharmacokinetics and Pharmacodynamics of Metformin. Clin Pharmacokinet 55:711-21
Yuan, Bo; Yoshino, Yuta; Fukushima, Hisayo et al. (2016) Multidrug resistance-associated protein 4 is a determinant of arsenite resistance. Oncol Rep 35:147-54

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