Clinical Studies Research will maintain SOPHIE, Studies Of Pharmacogenetcs in Ethnically Diverse Populations, a cohort of healthy volunteers who have agreed to be called back for further pharmacogenetic studies. This team will conduct mechanistic genotype driven clinical studies and participate in collaborative studies with PGRN investigators. Members of this team will lead our large clinical study focused on metformin, an anti-diabetic drug that interacts with multiple transporters

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Program--Cooperative Agreements (U19)
Project #
5U19GM061390-14
Application #
8546203
Study Section
Special Emphasis Panel (ZRG1-GGG-M)
Project Start
Project End
Budget Start
2013-07-01
Budget End
2014-06-30
Support Year
14
Fiscal Year
2013
Total Cost
$390,919
Indirect Cost
$89,036
Name
University of California San Francisco
Department
Type
DUNS #
094878337
City
San Francisco
State
CA
Country
United States
Zip Code
94143
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Martin, M A; Hoffman, J M; Freimuth, R R et al. (2014) Clinical Pharmacogenetics Implementation Consortium Guidelines for HLA-B Genotype and Abacavir Dosing: 2014 update. Clin Pharmacol Ther 95:499-500

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