The Computational Genomics Research Team will interact with the Functional Genomics Team to develop algorithms for predicting function of coding region variants and for analyzing expression levels and splice variant forms of transporters from RNAseq studies in kidney and liver banks. In addition, they will work together to identify potential regulatory regions of the membrane transporter genes. One of the approaches will be to generate a co-expression network and to construct a transcription network. The group will also expand their previous effort to define substrate specificity of membrane transporters and to develop predictive models for substrate-dependent effects of coding region variants.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Program--Cooperative Agreements (U19)
Project #
5U19GM061390-15
Application #
8689079
Study Section
Special Emphasis Panel (ZRG1-GGG-M)
Project Start
Project End
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
15
Fiscal Year
2014
Total Cost
$254,029
Indirect Cost
$61,322
Name
University of California San Francisco
Department
Type
DUNS #
094878337
City
San Francisco
State
CA
Country
United States
Zip Code
94143
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