This application requests five years of funding to sustain and expand the Mental Health Research Network (MHRN), a consortium of 13 research centers affiliated with large integrated health systems. Two new members will join the network, increasing the diversity of health system organization and adding a larger rural population. Established data and informatics infrastructure will be maintained (with reduced levels of funding). New infrastructure development will aim to address the opportunities and challenges described above and to address specific goals described in RFA MH-14-110: * Dissemination of MHRN tools and resources to the broader mental health research community * Facilitating new research collaborations with investigators outside of MHRN member institutions * Improving capacity for ongoing surveillance of mental health treatment patterns and outcomes MHRN will be governed by a steering committee of participating investigators and representatives from NIMH. An Administrative Core will house specific infrastructure activities, including: * The Informatics Unit will maintain and expand data infrastructure to support multi-site research. * The Organizational Unit will continue work to streamline administrative and regulatory processes. * The Outreach and External Collaboration Unit will continue engagement with health system partners and external stakeholders while expanding outreach to external investigators. Four specific research projects are proposed: * Reducing cardiovascular risk in adults with SMI using EMR-based clinical decision support - This cluster randomized trial will test an informatics-based intervention to reduce risk factors for cardiovascular disease among people living with severe mental illness. * Maximizing biospecimen collection from children with mental health conditions - This pilot study will evaluate strategies for collecting biospecimens from families affected by early-onset mental disorders. * Next-generation assessment using mobile devices - This pilot study will evaluate the feasibility, acceptability, and potential utility of direct assessment of behavior and neuropsychological performance (including NIMH RDoC constructs) for prediction or early detection of depression treatment response. * Automated outreach for depression treatment dropout - This pilot study will evaluate the feasibility and acceptability of population-based outreach to address early dropout from depression treatment.

Public Health Relevance

The MHRN was first funded in 2010 with the overall objective of improving the speed, efficiency, and generalizability of mental health clinical and health services research. This application requests five years of funding to sustain and expand the MHRN. Through a program of targeted infrastructure development and four specific research projects, the MHRN aims to become a national resource for patients, providers, health system leaders, and policy makers.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Program--Cooperative Agreements (U19)
Project #
3U19MH092201-04S1
Application #
8920952
Study Section
Special Emphasis Panel (ZMH1-ERB-B (02))
Program Officer
Chambers, David A
Project Start
2010-09-24
Project End
2019-06-30
Budget Start
2014-09-10
Budget End
2015-06-30
Support Year
4
Fiscal Year
2014
Total Cost
$302,802
Indirect Cost
$25,573
Name
Group Health Cooperative
Department
Type
DUNS #
078198520
City
Seattle
State
WA
Country
United States
Zip Code
98101
Coleman, Karen J; Johnson, Eric; Ahmedani, Brian K et al. (2018) Predicting Suicide Attempts for Racial and Ethnic Groups of Patients During Routine Clinical Care. Suicide Life Threat Behav :
Lu, Christine Y; Penfold, Robert B; Toh, Sengwee et al. (2018) Near Real-time Surveillance for Consequences of Health Policies Using Sequential Analysis. Med Care 56:365-372
Simon, Gregory E; Johnson, Eric; Lawrence, Jean M et al. (2018) Predicting Suicide Attempts and Suicide Deaths Following Outpatient Visits Using Electronic Health Records. Am J Psychiatry 175:951-960
Rossom, Rebecca C; Simon, Greg E; Coleman, Karen J et al. (2018) Are wishes for death or suicidal ideation symptoms of depression in older adults? Aging Ment Health :1-7
Lu, Christine Y; Simon, Gregory; Soumerai, Stephen B et al. (2018) Counter-Point: Early Warning Systems Are Imperfect, but Essential. Med Care 56:382-383
Lu, Christine Y; Simon, Gregory; Soumerai, Stephen B (2018) Counter-Point: Staying Honest When Policy Changes Backfire. Med Care 56:384-390
Waitzfelder, Beth; Stewart, Christine; Coleman, Karen J et al. (2018) Treatment Initiation for New Episodes of Depression in Primary Care Settings. J Gen Intern Med 33:1283-1291
Madden, Jeanne M; Lakoma, Matthew D; Lynch, Frances L et al. (2017) Psychotropic Medication Use among Insured Children with Autism Spectrum Disorder. J Autism Dev Disord 47:144-154
Hacker, Karen; Penfold, Robert; Arsenault, Lisa N et al. (2017) The Impact of the Massachusetts Behavioral Health Child Screening Policy on Service Utilization. Psychiatr Serv 68:25-32
Simon, Gregory E; Shortreed, Susan M; Johnson, Eric et al. (2017) Between-visit changes in suicidal ideation and risk of subsequent suicide attempt. Depress Anxiety 34:794-800

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