The purpose of this proposal is to develop an Implementation Science Resource Core to support the research efforts of several CHAART consortia, building upon existing infrastructure within these consortia. The current proposal would create the infrastructure to close the loop of the research cycle for NIAAA-funded research. ORCAAA (The Operations Research Collaboration for Alcohol Abuse and AIDS) would be a resource core using implementation science to inform decisions important to investigators, public health authorities, and clinician/patient dyads. In particular, ORCAAA will create 3 different PODS (Portals Of Decision Support) that will function as catalysts of collaboration, providing CHAART investigators with tailored decision support in order assure that research will be harnessed most effectively to improve population health. In particular the ORCAAA resource core will implement the following aims:
Aim 1 : Facilitate implementation of CHAART HIV/AIDS interventions targeting highest risk populations;
Aim 2 : Increase capacity for implementation science to impact CHAART study design;
Aim 3 : Increase capacity for evaluating effect of CHAART alcohol interventions on HIV progression

Public Health Relevance

Our proposal will substantially enhance the formulation of consortia directions and goals, and accelerate the progress of ongoing and future investigations by giving consortia access to resources, information, ideas, and expertise in Implementation Science that are otherwise beyond the scope of any single research team.

Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Resource-Related Research Projects--Cooperative Agreements (U24)
Project #
5U24AA022007-04
Application #
8901748
Study Section
Special Emphasis Panel (ZAA1)
Program Officer
Falk, Daniel
Project Start
2012-09-15
Project End
2016-08-31
Budget Start
2015-09-01
Budget End
2016-08-31
Support Year
4
Fiscal Year
2015
Total Cost
Indirect Cost
Name
New York University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
121911077
City
New York
State
NY
Country
United States
Zip Code
10016
Li, Lingfeng; Uyei, Jennifer; Nucifora, Kimberly A et al. (2018) Using value of information methods to determine the optimal sample size for effectiveness trials of alcohol interventions for HIV-infected patients in East Africa. BMC Health Serv Res 18:590
Justice, Amy C; Gordon, Kirsha S; Skanderson, Melissa et al. (2018) Nonantiretroviral polypharmacy and adverse health outcomes among HIV-infected and uninfected individuals. AIDS 32:739-749
Justice, Amy C; Gordon, Kirsha; Skanderson, Melissa et al. (2018) Non antiretroviral polypharmacy and adverse health outcomes among HIV-infected and uninfected individuals. AIDS :
Herrin, Melissa; Tate, Janet P; Akgün, Kathleen M et al. (2016) Weight Gain and Incident Diabetes Among HIV-Infected Veterans Initiating Antiretroviral Therapy Compared With Uninfected Individuals. J Acquir Immune Defic Syndr 73:228-36
Yin, Michael T; Shiau, Stephanie; Rimland, David et al. (2016) Fracture Prediction With Modified-FRAX in Older HIV-Infected and Uninfected Men. J Acquir Immune Defic Syndr 72:513-20
Salinas, Jorge L; Rentsch, Christopher; Marconi, Vincent C et al. (2016) Baseline, Time-Updated, and Cumulative HIV Care Metrics for Predicting Acute Myocardial Infarction and All-Cause Mortality. Clin Infect Dis 63:1423-1430
Rentsch, Christopher; Tate, Janet P; Akgün, Kathleen M et al. (2016) Erratum to: Alcohol-Related Diagnoses and All-Cause Hospitalization Among HIV-Infected and Uninfected Patients: A Longitudinal Analysis of United States Veterans from 1997 to 2011. AIDS Behav 20:565
Braithwaite, R Scott; Fang, Yixin; Tate, Janet et al. (2016) Do Alcohol Misuse, Smoking, and Depression Vary Concordantly or Sequentially? A Longitudinal Study of HIV-Infected and Matched Uninfected Veterans in Care. AIDS Behav 20:566-72
McGinnis, Kathleen A; Tate, Janet P; Williams, Emily C et al. (2016) Comparison of AUDIT-C collected via electronic medical record and self-administered research survey in HIV infected and uninfected patients. Drug Alcohol Depend 168:196-202
Rentsch, Christopher; Tate, Janet P; Akgün, Kathleen M et al. (2016) Alcohol-Related Diagnoses and All-Cause Hospitalization Among HIV-Infected and Uninfected Patients: A Longitudinal Analysis of United States Veterans from 1997 to 2011. AIDS Behav 20:555-64

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