Project Description: The RTOG recognizes the importance of a tissue resource of present and future correlative trials.
The specific aims of this tissue bank application are: (1) To acquire, store, and track blood, leukocytes and tissue samples from RTOG patients entered on Phase III clinical trials in compliance with policies and procedures of the Group Banking Committee of NCI. (2) To preserve the maximum amount of tissue in each sample by expert block, tissue array and sample preparation, by laser capture of appropriate tissue elements, and by appropriate tissue quality assurance. (3) To market, and distribute samples equitably to all qualified investigators by a standardized method developed or modified collaboratively with the Group Banking Committee of NCI.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Resource-Related Research Projects--Cooperative Agreements (U24)
Project #
3U24CA114734-05S1
Application #
8144083
Study Section
Special Emphasis Panel (ZCA1-SRRB-3 (J1))
Program Officer
Lubensky, Irina
Project Start
2005-09-14
Project End
2012-03-31
Budget Start
2009-05-20
Budget End
2012-03-31
Support Year
5
Fiscal Year
2010
Total Cost
$1,040,063
Indirect Cost
Name
American College of Radiology
Department
Type
DUNS #
062485800
City
Reston
State
VA
Country
United States
Zip Code
20191
Lawrence, Yaacov R; Moughan, Jennifer; Magliocco, Anthony M et al. (2018) Expression of the DNA repair gene MLH1 correlates with survival in patients who have resected pancreatic cancer and have received adjuvant chemoradiation: NRG Oncology RTOG Study 9704. Cancer 124:491-498
Farrell, James J; Moughan, Jennifer; Wong, Jonathan L et al. (2016) Precision Medicine and Pancreatic Cancer: A Gemcitabine Pathway Approach. Pancreas 45:1485-1493
Li, Donghui; Moughan, Jennifer; Crane, Christopher et al. (2016) RECQ1 A159C Polymorphism Is Associated With Overall Survival of Patients With Resected Pancreatic Cancer: A Replication Study in NRG Oncology Radiation Therapy Oncology Group 9704. Int J Radiat Oncol Biol Phys 94:554-60
Ben-Josef, Edgar; George, Asha; Regine, William F et al. (2015) Glycogen Synthase Kinase 3 Beta Predicts Survival in Resected Adenocarcinoma of the Pancreas. Clin Cancer Res 21:5612-8
Rabinovitch, Rachel; Winter, Kathryn; Kuske, Robert et al. (2014) RTOG 95-17, a Phase II trial to evaluate brachytherapy as the sole method of radiation therapy for Stage I and II breast carcinoma--year-5 toxicity and cosmesis. Brachytherapy 13:17-22
Kunos, Charles A; Winter, Kathryn; Dicker, Adam P et al. (2013) Ribonucleotide reductase expression in cervical cancer: a radiation therapy oncology group translational science analysis. Int J Gynecol Cancer 23:615-21
Roach 3rd, Mack; Waldman, Fred; Pollack, Alan (2009) Predictive models in external beam radiotherapy for clinically localized prostate cancer. Cancer 115:3112-20
Woodward, Wendy A; Bristow, Robert G; Clarke, Michael F et al. (2009) Radiation Therapy Oncology Group translational research program stem cell symposium: incorporating stem cell hypotheses into clinical trials. Int J Radiat Oncol Biol Phys 74:1580-91