The main goal of the UC MMPC is to continue providing phenotyping services related to diabetes and its complications in numerous transgenic and knockout mouse models, to investigators from all over the United States, both young and seasoned. To achieve this goal, the UC MMPC is comprised of three phenotyping Service Cores, plus one animal husbandry Core to coordinate issues related to the health, shipping, and husbandry of the mice. While these four Cores work extremely well together, it is the Administrative Core (Core A) that plays a pivotal role in making sure that investigators'requests are being processed and that the Service Cores are working smoothly and efficiently to provide phenotyping data to investigators. In addition, Core A is also responsible for coordinating visits by outside investigators to come to the UC MMPC to learn surgical technique or procedures. The key personnel associated with Core A have been working together closely for the last nine and a half years and interact on a daily basis to manage these needs of the UC MMPC. There are four specific aims for this Core:
Specific Aim 1 : To coordinate service requests from investigators with the appropriate Service Cores, and to make sure that each request is dealt with professionally and adequately.
Specific Aim 2 : To manage the data yielded by the Service Cores so it goes through statistical analyses, is entered into both the UC MMPC Data Base and the CBU Data Base, and the billing and collection of funds generated by the UC MMPC.
Specific Aim 3 : To coordinate the monthly MMPC Executive Committee Meetings, as well as the Semi-Annual Advisory Committee Meetings and the MMPC Seminar Series.
Specific Aim 4 : To track the acknowledgements and publications associated with the UC MMPC.
It is the Administrative Core that plays a pivotal role in making sure that investigators'requests are being processed and that the Service Cores are working smoothly and efficiently to provide phenotyping data to investigators. Additionally this Core is responsible for reporting data to the investigator and uploading the data to the UC MMPC Data Base and the CBU Data Base.
|McNamara, Robert K; Jandacek, Ronald; Rider, Therese et al. (2016) Effects of fish oil supplementation on prefrontal metabolite concentrations in adolescents with major depressive disorder: a preliminary 1H MRS study. Nutr Neurosci 19:145-55|
|Costa, Diana K; Huckestein, Brydie R; Edmunds, Lia R et al. (2016) Reduced intestinal lipid absorption and body weight-independent improvements in insulin sensitivity in high-fat diet-fed Park2 knockout mice. Am J Physiol Endocrinol Metab 311:E105-16|
|Zhang, Wenwei; Bu, So Young; Mashek, Mara T et al. (2016) Integrated Regulation of Hepatic Lipid and Glucose Metabolism by Adipose Triacylglycerol Lipase and FoxO Proteins. Cell Rep 15:349-59|
|Song, Chi Young; Ghafoor, Khuzema; Ghafoor, Hafiz U et al. (2016) Cytochrome P450 1B1 Contributes to the Development of Atherosclerosis and Hypertension in Apolipoprotein E-Deficient Mice. Hypertension 67:206-13|
|Rider, T; LeBoeuf, R C; Tso, Patrick et al. (2016) The Use of Kits in the Analysis of Tissue Lipids Requires Validation. Lipids 51:497-504|
|McNamara, Robert K; Jandacek, Ronald; Tso, Patrick et al. (2016) Adolescents with or at ultra-high risk for bipolar disorder exhibit erythrocyte docosahexaenoic acid and eicosapentaenoic acid deficits: a candidate prodromal risk biomarker. Early Interv Psychiatry 10:203-11|
|Zhang, Linda S; Xu, Min; Yang, Qing et al. (2015) Apolipoprotein A-V deficiency enhances chylomicron production in lymph fistula mice. Am J Physiol Gastrointest Liver Physiol 308:G634-42|
|Harris, Devon; Liang, Yuanyuan; Chen, Cang et al. (2015) Bone marrow from blotchy mice is dispensable to regulate blood copper and aortic pathologies but required for inflammatory mediator production in LDLR-deficient mice during chronic angiotensin II infusion. Ann Vasc Surg 29:328-40|
|Stuart, William D; Brown, Nicholas E; Paluch, Andrew M et al. (2015) Loss of Ron receptor signaling leads to reduced obesity, diabetic phenotypes and hepatic steatosis in response to high-fat diet in mice. Am J Physiol Endocrinol Metab 308:E562-72|
|Yao, Jessica; Qin, Zhenyu (2015) Counteract of bone marrow of blotchy mice against the increases of plasma copper levels induced by high-fat diets in LDLR-/- mice. J Trace Elem Med Biol 31:11-7|
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