The main goal of the UC MMPC is to continue providing phenotyping services related to diabetes and its complications in numerous transgenic and knockout mouse models, to investigators from all over the United States, both young and seasoned. To achieve this goal, the UC MMPC is comprised of three phenotyping Service Cores, plus one animal husbandry Core to coordinate issues related to the health, shipping, and husbandry of the mice. While these four Cores work extremely well together, it is the Administrative Core (Core A) that plays a pivotal role in making sure that investigators'requests are being processed and that the Service Cores are working smoothly and efficiently to provide phenotyping data to investigators. In addition, Core A is also responsible for coordinating visits by outside investigators to come to the UC MMPC to learn surgical technique or procedures. The key personnel associated with Core A have been working together closely for the last nine and a half years and interact on a daily basis to manage these needs of the UC MMPC. There are four specific aims for this Core:
Specific Aim 1 : To coordinate service requests from investigators with the appropriate Service Cores, and to make sure that each request is dealt with professionally and adequately.
Specific Aim 2 : To manage the data yielded by the Service Cores so it goes through statistical analyses, is entered into both the UC MMPC Data Base and the CBU Data Base, and the billing and collection of funds generated by the UC MMPC.
Specific Aim 3 : To coordinate the monthly MMPC Executive Committee Meetings, as well as the Semi-Annual Advisory Committee Meetings and the MMPC Seminar Series.
Specific Aim 4 : To track the acknowledgements and publications associated with the UC MMPC.

Public Health Relevance

It is the Administrative Core that plays a pivotal role in making sure that investigators'requests are being processed and that the Service Cores are working smoothly and efficiently to provide phenotyping data to investigators. Additionally this Core is responsible for reporting data to the investigator and uploading the data to the UC MMPC Data Base and the CBU Data Base.

National Institute of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Resource-Related Research Projects--Cooperative Agreements (U24)
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Special Emphasis Panel (ZDK1-GRB-S)
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University of Cincinnati
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Harley, Isaac T W; Stankiewicz, Traci E; Giles, Daniel A et al. (2014) IL-17 signaling accelerates the progression of nonalcoholic fatty liver disease in mice. Hepatology 59:1830-9
Wang, Fei; Kohan, Alison B; Dong, H Henry et al. (2014) Overexpression of apolipoprotein C-III decreases secretion of dietary triglyceride into lymph. Physiol Rep 2:e00247
Poole, Daniel P; Lee, Mike; Tso, Patrick et al. (2014) Feeding-dependent activation of enteric cells and sensory neurons by lymphatic fluid: evidence for a neurolymphocrine system. Am J Physiol Gastrointest Liver Physiol 306:G686-98
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McNamara, Robert K; Strimpfel, Jennifer; Jandacek, Ronald et al. (2014) Detection and Treatment of Long-Chain Omega-3 Fatty Acid Deficiency in Adolescents with SSRI-Resistant Major Depressive Disorder. PharmaNutrition 2:38-46
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