The Southeast Resource Center for Integrated Metabolomics (SECIM) integrates existing strengths to create a comprehensive resource for basic and clinical scientists to obtain state-of-the-art metabolomics data and analyses. The SECIM Promotion and Outreach (P&O) Core is co-directed by Dr. Steven Smith, a clinical investigator and Scientific Director ofthe Sanford-Burnham Translational Research Institute in Orlando, and Dr. Michael Conlon, Chief Operating Officer of the UF CTSI and PI of VIVO, a system for scholarly networking and discovery. P&O is responsible for connecting users to SECIM services and science, and it has established several aims to accomplish this goal. P&O will establish the SECIM brand by establishing web-based and social media outreach, building new institutional collaborations and a larger user base, and ensuring that SECIM is represented at major meetings and conferences. P&O will coordinate educational activities that will train new users in the analytical tools and analysis offered by SECIM. This will include the development of online educational resources as well as the annual SECIM Metabolomics Workshop, which will include general introductions to technologies as well as more focused offerings for specific groups, such as bioinformatics for biologists or clinicians. These workshops represent a critical interface between SECIM analytical cores, bioinformatics, and users. Pilot &Feasibility (P&F) projects will be administered through the P&O Core, which will capture all metrics such as publications, meeting presentations, new grants, etc., for both P&F projects and general SECIM users. The funds available for P&F projects are significantly enhanced through matching funds from several groups at UF, allowing more studies to be done through SECIM in the early years of growth. The P&F projects are a core component ofthe SECIM business model, as described in the Administrative Core. P&O will help to connect the network of SECIM users to enhance the biomedical impact of metabolomics research.

Public Health Relevance

The major goal of metabolomics is the measurement and characterization of metabolites from living organisms, including people. Small molecule metabolites are sensitive to disease, treatment, and many environmental factors, and they can be used as indicators of disease in diagnosis or as markers to assess the outcome of treatment.

Project Start
Project End
Budget Start
2014-09-01
Budget End
2015-08-31
Support Year
2
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of Florida
Department
Type
DUNS #
City
Gainesville
State
FL
Country
United States
Zip Code
32611
Walejko, Jacquelyn M; Kim, Seungbum; Goel, Ruby et al. (2018) Gut microbiota and serum metabolite differences in African Americans and White Americans with high blood pressure. Int J Cardiol 271:336-339
Walejko, Jacquelyn M; Koelmel, Jeremy P; Garrett, Timothy J et al. (2018) Multi-omics Approach Reveals Metabolic Changes in the Heart at Birth. Am J Physiol Endocrinol Metab :
Wu, Cheng-Yang; Satapati, Santhosh; Gui, Wenjun et al. (2018) A novel inhibitor of pyruvate dehydrogenase kinase stimulates myocardial carbohydrate oxidation in diet-induced obesity. J Biol Chem 293:9604-9613
Chouinard, Christopher D; Cruzeiro, Vinicius Wilian D; Kemperman, Robin H J et al. (2018) Cation-Dependent Conformations in 25-Hydroxyvitamin D3-Cation Adducts Measured by Ion Mobility-Mass Spectrometry and Theoretical Modeling. Int J Mass Spectrom 432:1-8
Sirusi, Ali A; Suh, Eul Hyun; Kovacs, Zoltan et al. (2018) The effect of Ho3+ doping on 13C dynamic nuclear polarization at 5 T. Phys Chem Chem Phys 20:728-731
Costford, Sheila R; Brouwers, Bram; Hopf, Meghan E et al. (2018) Skeletal muscle overexpression of nicotinamide phosphoribosyl transferase in mice coupled with voluntary exercise augments exercise endurance. Mol Metab 7:1-11
Lewis, Samantha L; Holl, Heather M; Long, Maureen T et al. (2018) Use of principle component analysis to quantitatively score the equine metabolic syndrome phenotype in an Arabian horse population. PLoS One 13:e0200583
Ulmer, Candice Z; Jones, Christina M; Yost, Richard A et al. (2018) Optimization of Folch, Bligh-Dyer, and Matyash sample-to-extraction solvent ratios for human plasma-based lipidomics studies. Anal Chim Acta 1037:351-357
Zhao, Qi; Shen, Hui; Su, Kuan-Jui et al. (2018) A joint analysis of metabolomic profiles associated with muscle mass and strength in Caucasian women. Aging (Albany NY) 10:2624-2635
Lyon, Debra E; Starkweather, Angela; Yao, Yingwei et al. (2018) Pilot Study of Metabolomics and Psychoneurological Symptoms in Women With Early Stage Breast Cancer. Biol Res Nurs 20:227-236

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