The proposed NHGRI Genome Sequencing Program Coordinating Center (GSPCC) will provide centralized and collaborative program coordination and scientific leadership to the Centers for Complex Disease Genomics (CCDG) and the Centers for Mendelian Genomics (CMG). The GSPCC will lead an analysis to evaluate when a common disease variant discovery study is effectively complete, develop specifications for a set of common controls for common disease rare variant studies, produce allele frequency data for the CMG program, and provide input into other cross-program activities as needed. The GSPCC will also coordinate logistics, communication, and outreach activities including scheduling and running meetings and teleconferences, hosting websites for data distribution and dissemination of project information to the public, and organizing other efforts as needed by the GSP. Coordination of the program will be done in a spirit of collaboration using creative, flexible, impartial approaches. Throughout the project the GSPCC will work with the funded GSP centers, the steering committee and the NHGRI to help facilitate a comprehensive and successful program of research to meet the goals of the GSP in promoting discovery of disease-related variants and identification of their potential causal roles. Our collaborative CC team is ideally staffed to meet the needs of the GSPCC.

Public Health Relevance

The NHGRI Genome Sequencing Program promotes the discovery of disease-related genetic variants and identification of their causal roles. We propose to serve as the Genome Sequencing Program Coordinating Center (GSPCC) by providing scientific leadership for specific cross-program objectives and program coordination for administrative, logistical, and outreach activities. Our team has the expertise and infrastructure in place to facilitate completion of a comprehensive program of research that will meet the goals for the Genome Sequencing Program.

Agency
National Institute of Health (NIH)
Institute
National Human Genome Research Institute (NHGRI)
Type
Resource-Related Research Projects--Cooperative Agreements (U24)
Project #
5U24HG008956-04
Application #
9608764
Study Section
Special Emphasis Panel (ZHG1)
Program Officer
Felsenfeld, Adam
Project Start
2016-01-14
Project End
2019-11-30
Budget Start
2018-12-01
Budget End
2019-11-30
Support Year
4
Fiscal Year
2019
Total Cost
Indirect Cost
Name
Rutgers University
Department
Genetics
Type
Schools of Arts and Sciences
DUNS #
001912864
City
Piscataway
State
NJ
Country
United States
Zip Code
08854
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