This proposal for a Phase II International Clinical, Operational and Health Services Research Training Award for AIDS and Tuberculosis (ICOHRTA-AIDS/TB) is based upon the research training needs and opportunities identified during the Phase I ICOHRTA-AIDS/TB planning grant in Peru. Participant institutions in the Phase I grant and this Phase II proposal have a well-established collaborative research and research training history in Peru: Universidad Peruana Cayetano Heredia (UPCH);University of Washington (UW);University of Alabama at Birmingham (UAB);and the Peruvian research NGO IMPACTA. The overarching goals of this ICOHRTA-AIDS/TB program are to preserve the health of people living with HIV/AIDS;provide timely, curative treatment to persons with tuberculosis;and decrease transmission of these infections. To achieve these goals, we propose the development of an ICOHRTA research training program at UPCH to increase the cadre of Peruvian and other Latin American scientists active in clinical, operational, and health services research in HIV/AIDS and TB;and to catalyze and guide the application of research expertise in Latin America for scale-up, cost-effective delivery, and continuous improvement of treatment, care, and prevention services for HIV/AIDS and TB. Specific activities will include: 1) implementation of an innovative, locally-directed educational curriculum at UPCH to underpin the ICOHRTA-AIDS/TB program, including the development of a Graduate Certificate Program in HIV/AIDS and TB at UPCH, focused on clinical, operational, and health services research and related prevention research;2) training, mentoring and small grants for Graduate Certificate Program trainees to perform clinical, operational, and health services research and related prevention research for treatment, care and prevention of HIV/AIDS and TB;3) Provide long term research and training experience and career mentoring for current or potential UPCH faculty members. This ICOHRTA proposal would enhance not only the sustainability of the existing collaborative research training efforts in Peru, but also the relevance of research training to local needs and opportunities as HIV/AIDS and TB treatment and prevention efforts are scaled up in Peru and other Andean countries.

Agency
National Institute of Health (NIH)
Institute
Fogarty International Center (FIC)
Type
International Research Training Cooperative Agreements (U2R)
Project #
5U2RTW007368-05
Application #
8109339
Study Section
Special Emphasis Panel (ZRG1-ICP2-B (51))
Program Officer
Mcdermott, Jeanne
Project Start
2007-08-01
Project End
2014-05-31
Budget Start
2011-06-01
Budget End
2014-05-31
Support Year
5
Fiscal Year
2011
Total Cost
$365,825
Indirect Cost
Name
Universidad Peruana Cayetano Heredia
Department
Type
DUNS #
934798430
City
Lima
State
Country
Peru
Zip Code
LIMA -31
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Valenzuela, Carla; Ugarte-Gil, Cesar; Paz, Jorge et al. (2015) HIV stigma as a barrier to retention in HIV care at a general hospital in Lima, Peru: a case-control study. AIDS Behav 19:235-45
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Alave, Jorge; Paz, Jorge; González, Elsa et al. (2013) [Risk factors associated with virologic failure in HIV- infected patients receiving antiretroviral therapy at a public hospital in Peru]. Rev Chilena Infectol 30:42-8
Mendoza-Ticona, Alberto; Moore, David A J; Alarcón, Valentina et al. (2013) [Proposal of anti-tuberculosis regimens based on susceptibility to isoniazid and rifampicin]. Rev Peru Med Exp Salud Publica 30:197-204
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Carriquiry, Gabriela; Otero, Larissa; González-Lagos, Elsa et al. (2012) A diagnostic accuracy study of Xpert®MTB/RIF in HIV-positive patients with high clinical suspicion of pulmonary tuberculosis in Lima, Peru. PLoS One 7:e44626
Alave, Jorge; Bustamante, Beatriz; Soto, Leslie et al. (2011) Acalculous Cholecystitis caused by Histoplasma capsulatum in a severely immunosuppressed HIV-infected patient. J Infect Dev Ctries 5:235-8
León, Mey; Alave, Jorge; Martinez, Dalila et al. (2011) Symptomatic duodenal cryptococcosis in HIV-infected individuals. Med Mycol 49:775-8

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