The goal of the Saccharomyces Genome Database (SGD) is to continue the development and implementation of a comprehensive resource containing curated information about the genome and its elements of the budding yeast, Saccharomyces cerevisiae. SGD will continue to annotate the genome, assimilate new data, include genomic information from other fungal species, and incorporate formalized and controlled vocabularies to represent biological concepts. We will continue to maintain and broaden relationships with the greater scientific community and make technical improvements through the development of tools and the use of third party tools that will allow us to better serve our users. The database and its associated resources will always remain publicly available without restriction from www.yeastgenome.org. SGD will continue to provide the S. cerevisiae genome and its gene products culled from the published literature. New user interfaces and analysis resources will be developed for existing information as well as for new types of data, such as results from large scale genomic/proteomic analysis. These improvements will be developed using publicly available tools such as those available from the GMOD project. Query tools will be more enhanced to instantly direct users to the appropriate pages. SGD has evolved into a substantial service organization, and will maintain its service to the scientific community, reaching out to all yeast researchers as well as scientists outside the fungal community to serve those who have a need for information about budding yeast genes, their products, and their functions. SGD will continue existing services while working to simplify the use and maintenance of our hardware and software environment through the application of new technologies. We will continue to collaborate with the yeast biology community to keep the database accurate and current, and to maintain consensus and order in the naming of genes and other generic elements.

Public Health Relevance

Saccharomyces cerevisiae is a model forth understanding of chromosome maintenance, the cell cycle and cellular biology. S. cerevisiae is used for the development of new genomic and proteomic technologies. S. cerevisiae is the most well studied eukaryofic genome and the experimental literature for this yeast contains these results. The SGD provides a comprehensive resource that facilitates experimentation in other systems,

Agency
National Institute of Health (NIH)
Institute
National Human Genome Research Institute (NHGRI)
Type
Biotechnology Resource Cooperative Agreements (U41)
Project #
5U41HG001315-19
Application #
8447583
Study Section
Special Emphasis Panel (ZHG1-HGR-M (O2))
Program Officer
Bonazzi, Vivien
Project Start
1995-09-30
Project End
2016-02-29
Budget Start
2013-03-01
Budget End
2014-02-28
Support Year
19
Fiscal Year
2013
Total Cost
$2,703,817
Indirect Cost
$1,213,614
Name
Stanford University
Department
Genetics
Type
Schools of Medicine
DUNS #
009214214
City
Stanford
State
CA
Country
United States
Zip Code
94305
Engel, Stacia R; Weng, Shuai; Binkley, Gail et al. (2016) From one to many: expanding the Saccharomyces cerevisiae reference genome panel. Database (Oxford) 2016:
Song, Giltae; Balakrishnan, Rama; Binkley, Gail et al. (2016) Integration of new alternative reference strain genome sequences into the Saccharomyces genome database. Database (Oxford) 2016:
Sheppard, Travis K; Hitz, Benjamin C; Engel, Stacia R et al. (2016) The Saccharomyces Genome Database Variant Viewer. Nucleic Acids Res 44:D698-702
Skrzypek, Marek S; Nash, Robert S (2015) Biocuration at the Saccharomyces genome database. Genesis 53:450-7
Cherry, J Michael (2015) The Saccharomyces Genome Database: Advanced Searching Methods and Data Mining. Cold Spring Harb Protoc 2015:pdb.prot088906
Meldal, Birgit H M; Forner-Martinez, Oscar; Costanzo, Maria C et al. (2015) The complex portal--an encyclopaedia of macromolecular complexes. Nucleic Acids Res 43:D479-84
Cherry, J Michael (2015) The Saccharomyces Genome Database: Gene Product Annotation of Function, Process, and Component. Cold Spring Harb Protoc 2015:pdb.prot088914
Cherry, J Michael (2015) The Saccharomyces Genome Database: Exploring Biochemical Pathways and Mutant Phenotypes. Cold Spring Harb Protoc 2015:pdb.prot088898
Cherry, J Michael (2015) The Saccharomyces Genome Database: A Tool for Discovery. Cold Spring Harb Protoc 2015:pdb.top083840
Cherry, J Michael (2015) The Saccharomyces Genome Database: Exploring Genome Features and Their Annotations. Cold Spring Harb Protoc 2015:pdb.prot088922

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