This subproject is one of many research subprojects utilizing theresources provided by a Center grant funded by NIH/NCRR. The subproject andinvestigator (PI) may have received primary funding from another NIH source,and thus could be represented in other CRISP entries. The institution listed isfor the Center, which is not necessarily the institution for the investigator.Overall Goal: To design, perform, and lead state of the art image MR-Guided therapy and procedures. The overarching vision for this core is to allow the simultaneous combination of direct vision and beyond the surface imaging is possible within a unique environment incorporating both the operating room and an MRI scanner. This allows for multimodal imaging to be visualized in real time with simultaneous inventions delivered and directly targeted in the operating room. Therapy delivery and effect can be directly monitored to ensure safe and effective results.This MRT Core is central to many of the other TRD Cores described in this application. The clinical applications in neurosurgery, prostate disease and general abdominal and musculoskeletal I intervention include procedures that would benefit from precise target spatial localization, computer navigation with or without fusion of imaging data sets, and temperature mapping.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Biotechnology Resource Cooperative Agreements (U41)
Project #
5U41RR019703-04
Application #
7719653
Study Section
Special Emphasis Panel (ZRG1-SBIB-L (40))
Project Start
2008-08-01
Project End
2009-07-31
Budget Start
2008-08-01
Budget End
2009-07-31
Support Year
4
Fiscal Year
2008
Total Cost
$149,587
Indirect Cost
Name
Brigham and Women's Hospital
Department
Type
DUNS #
030811269
City
Boston
State
MA
Country
United States
Zip Code
02115
Schmidt, Ehud J; Halperin, Henry R (2018) MRI use for atrial tissue characterization in arrhythmias and for EP procedure guidance. Int J Cardiovasc Imaging 34:81-95
George, E; Liacouras, P; Lee, T C et al. (2017) 3D-Printed Patient-Specific Models for CT- and MRI-Guided Procedure Planning. AJNR Am J Neuroradiol 38:E46-E47
Mitsouras, Dimitris; Lee, Thomas C; Liacouras, Peter et al. (2017) Three-dimensional printing of MRI-visible phantoms and MR image-guided therapy simulation. Magn Reson Med 77:613-622
Guenette, Jeffrey P; Himes, Nathan; Giannopoulos, Andreas A et al. (2016) Computer-Based Vertebral Tumor Cryoablation Planning and Procedure Simulation Involving Two Cases Using MRI-Visible 3D Printing and Advanced Visualization. AJR Am J Roentgenol 207:1128-1131
Mitsouras, Dimitris; Mulkern, Robert V; Maier, Stephan E (2016) Multicomponent T2 relaxation studies of the avian egg. Magn Reson Med 75:2156-64
Li, Mao; Miller, Karol; Joldes, Grand Roman et al. (2016) Biomechanical model for computing deformations for whole-body image registration: A meshless approach. Int J Numer Method Biomed Eng 32:
Schmidt, Ehud J; Watkins, Ronald D; Zviman, Menekhem M et al. (2016) A Magnetic Resonance Imaging-Conditional External Cardiac Defibrillator for Resuscitation Within the Magnetic Resonance Imaging Scanner Bore. Circ Cardiovasc Imaging 9:
Patil, Vaibhav; Gupta, Rajiv; San José Estépar, Raúl et al. (2015) Smart stylet: the development and use of a bedside external ventricular drain image-guidance system. Stereotact Funct Neurosurg 93:50-8
Garlapati, Revanth Reddy; Mostayed, Ahmed; Joldes, Grand Roman et al. (2015) Towards measuring neuroimage misalignment. Comput Biol Med 64:12-23
Lu, Yi; Yeung, Cecil; Radmanesh, Alireza et al. (2015) Comparative effectiveness of frame-based, frameless, and intraoperative magnetic resonance imaging-guided brain biopsy techniques. World Neurosurg 83:261-8

Showing the most recent 10 out of 261 publications