The University of California (UC) Davis Nonhuman Primate Testing Center for Evaluation of Somatic Cell Genome Editing Tools will support studies in nonhuman primates that will advance the genome editing field, and significantly contribute to the future translation of these technologies for the treatment of human disease. The Nonhuman Primate Testing Center brings together a robust team of multidisciplinary investigators with campus partnerships that capitalize on major strengths at UC Davis including the California National Primate Research Center, Genome Center, and Clinical and Translational Science Center. The Nonhuman Primate Testing Center will offer state-of-the-art capabilities for Somatic Cell Genome Editing (SCGE) awardees to conduct high quality research in nonhuman primates. The Nonhuman Primate Testing Center leverages a supportive framework that has demonstrated a long-standing commitment to providing research opportunities and collaborations to investigators nationwide. Through this powerful infrastructure the Nonhuman Primate Testing Center proposes the following Specific Aims: (1) Provide an administrative and organizational structure to advance somatic cell genome editing studies in nonhuman primates, (2) Foster partnerships with SCGE awardees through provision of resources that accelerate their research, and (3) Ensure synergism across the SCGE Program and Consortium via transparent interactions with the Dissemination and Coordinating Center, SCGE Working Group and Program Steering Committee, and the NIH. Our robust multidisciplinary team is poised to bring the depth and breadth of the UC Davis Nonhuman Primate Testing Center for Evaluation of Somatic Cell Genome Editing Tools to support SCGE investigators nationwide and contribute substantially to the Common Fund SCGE Program.

Public Health Relevance

The UC Davis Nonhuman Primate Testing Center for Evaluation of Somatic Cell Genome Editing Tools will serve the Somatic Cell Genome Editing community and the public by supporting studies in nonhuman primates that will advance the field. Through these efforts the Nonhuman Primate Testing Center will significantly contribute to the future translation of cutting-edge technologies for the treatment of a range of rare and common human diseases.

Agency
National Institute of Health (NIH)
Institute
Office of The Director, National Institutes of Health (OD)
Type
Animal (Mammalian and Nonmammalian) Model, and Animal and Biological Materials Resource Cooperative Agreements (U42)
Project #
1U42OD027094-01
Application #
9770048
Study Section
Special Emphasis Panel (ZRG1)
Program Officer
Mirochnitchenko, Oleg
Project Start
2019-04-15
Project End
2024-03-31
Budget Start
2019-04-15
Budget End
2020-03-31
Support Year
1
Fiscal Year
2019
Total Cost
Indirect Cost
Name
University of California Davis
Department
Pediatrics
Type
Schools of Medicine
DUNS #
047120084
City
Davis
State
CA
Country
United States
Zip Code
95618