Establishment of Adenoviral Vector Production Lab at Baylor

Brenner, Malcolm K.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Center for Research Resources (NCRR)
• Type: Animal (Mammalian and Nonmammalian) Model, and Animal and Biological Materials Resource Cooperative Agreements (U42)
• Project #: 5U42RR016578-04
• Application #: 6982942
• Study Section: Special Emphasis Panel (ZRR1-CR-4 (01))
• Project Start: 2004-09-01
• Project End: 2005-08-31
• Budget Start: 2004-09-01
• Budget End: 2005-08-31
• Support Year: 4
• Fiscal Year: 2004
• Total Cost: $611,343

Institution

• Name: Baylor College of Medicine
• Department: Pediatrics
• Type: Schools of Medicine
• DUNS #: 051113330
• City: Houston
• State: TX
• Country: United States
• Zip Code: 77030

Publications

Bollard, Catherine M; Gottschalk, Stephen; Torrano, Vicky et al. (2014) Sustained complete responses in patients with lymphoma receiving autologous cytotoxic T lymphocytes targeting Epstein-Barr virus latent membrane proteins. J Clin Oncol 32:798-808

Brenner, Malcolm K; Gottschalk, Stephen; Leen, Ann M et al. (2013) Is cancer gene therapy an empty suit? Lancet Oncol 14:e447-e456

Sili, Uluhan; Leen, Ann M; Vera, Juan F et al. (2012) Production of good manufacturing practice-grade cytotoxic T lymphocytes specific for Epstein-Barr virus, cytomegalovirus and adenovirus to prevent or treat viral infections post-allogeneic hematopoietic stem cell transplant. Cytotherapy 14:7-11

Bonini, Chiara; Brenner, Malcolm K; Heslop, Helen E et al. (2011) Genetic modification of T cells. Biol Blood Marrow Transplant 17:S15-20

Bollard, Catherine M; Gottschalk, Stephen; Helen Huls, M et al. (2011) Good manufacturing practice-grade cytotoxic T lymphocytes specific for latent membrane proteins (LMP)-1 and LMP2 for patients with Epstein-Barr virus-associated lymphoma. Cytotherapy 13:518-22

Ahmed, Nabil; Heslop, Helen E; Mackall, Crystal L (2010) T-cell-based therapies for malignancy and infection in childhood. Pediatr Clin North Am 57:83-96

Leen, Ann M; Christin, Anne; Myers, Gary D et al. (2009) Cytotoxic T lymphocyte therapy with donor T cells prevents and treats adenovirus and Epstein-Barr virus infections after haploidentical and matched unrelated stem cell transplantation. Blood 114:4283-92

Fujita, Yuriko; Leen, Ann M; Sun, Jiali et al. (2008) Exploiting cytokine secretion to rapidly produce multivirus-specific T cells for adoptive immunotherapy. J Immunother 31:665-74

Leen, Ann M; Christin, Anne; Khalil, Mariam et al. (2008) Identification of hexon-specific CD4 and CD8 T-cell epitopes for vaccine and immunotherapy. J Virol 82:546-54

Bollard, Catherine M; Gottschalk, Stephen; Leen, Ann M et al. (2007) Complete responses of relapsed lymphoma following genetic modification of tumor-antigen presenting cells and T-lymphocyte transfer. Blood 110:2838-45