FOR CENTER APPLICATION (provided by the investigator): Since 1998, the Yale-Griffin Prevention Research Center has been dedicated to conducting research pertaining to the I?, 2?, and 3?- prevention of chronic disease;to participatory research methods;to a robust research agenda inclusive of developmental/determinant, intervention, and translational research;to community involvement in public health;to the eradication of disparities in health/health care in the communities served;and to the dissemination of effective interventions in support of the national objectives of Healthy People 2010/20. In that span, the Center has acquired over $8 million in project grants beyond CDC core funding;run more than 60 trials;and generated 87 publications. Staff has grown from 5 to 16, and facilities have expanded from 1,200 to 3,600 square feet;the Center houses dedicated Research, Administrative/Infrastructure, Evaluation, Training, Community Engagement/Partnerships, and Communication/Dissemination Cores to support its work. The breadth of partnerships has grown tremendously over the past ten years through the active participation of Community Committee members, Community Action Teams, study participants and partners. Since its inception, the Center has placed particular emphasis on diabetes, obesity, and health disparities, with studies in four key content areas: lifestyle modification (1? prevention), including behavior change and environmental reform;and health care system modification (2? and 3? prevention), including clinical preventive service delivery and chronic disease management. Over the next 5 years, the center will build on successes to date, and on its extensive array of partnerships, to expand its community-based research agenda with increasing service to all of Connecticut and beyond via the PRC network. The Center will continue addressing disparities in major cities, particularly New Haven, whereas preserving close ties with the Lower Naugatuck Valley community. Core funds will support staff, infrastructure and advancing development of the TRIPOD (Translational Research Initiatives for the Prevention of Obesity and Diabetes) initiative, a program of diabetes/obesity prevention and control for use by the PRC network nationwide. Following 10 years of growth, expansion and gratifying productivity, the Center is poised to become an even more vital contributor to Connecticut, and the nation.

National Institute of Health (NIH)
National Center for Chronic Disease Prev and Health Promo (NCCDPHP)
Health Promotion and Disease Prevention Research Centers (U48)
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Special Emphasis Panel (ZCD1-CJM (06))
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Sims, Joyner
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Yale University
Public Health & Prev Medicine
Schools of Medicine
New Haven
United States
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Njike, Valentine Yanchou; Ayettey, Rockiy; Petraro, Paul et al. (2015) Walnut ingestion in adults at risk for diabetes: effects on body composition, diet quality, and cardiac risk measures. BMJ Open Diabetes Res Care 3:e000115
Doughty, Kimberly N; Njike, Valentine Yanchou; Katz, David L (2015) Effects of a cognitive-behavioral therapy-based immersion obesity treatment program for adolescents on weight, fitness, and cardiovascular risk factors: a pilot study. Child Obes 11:215-8
Katz, David L; Treu, Judith A; Ayettey, Rockiy G et al. (2014) Testing the effectiveness of an abbreviated version of the Nutrition Detectives program. Prev Chronic Dis 11:E57
Katz, David L (2014) Diet and diabetes: lines and dots. J Nutr 144:567S-570S
Sarrel, Philip M; Njike, Valentine Y; Vinante, Valentina et al. (2013) The mortality toll of estrogen avoidance: an analysis of excess deaths among hysterectomized women aged 50 to 59 years. Am J Public Health 103:1583-8
Reynolds, Jesse S; Treu, Judith A; Njike, Valentine et al. (2012) The validation of a food label literacy questionnaire for elementary school children. J Nutr Educ Behav 44:262-6