The Career Development and Training Program, directed by Developmental Director Water Stamm MD of the Administrative Core will be used by the NWRCE to increase the number and quality of basic and clinical researchers working in biodefense and emerging infectious in Region X (WA, OR, AK, ID). Promising scientists at the postdoctoral, junior faculty or senior faculty levels throughout Region X who are committed to pursuing a career in biodefense research will be 1) recruited and 2) supported by a one to three year career development award. The purpose of this funding mechanism is to make individuals competitive for other types of research funding for work on pathogens of national interest. Funds will provide for two types of programs within the Career Development plan;the Individual Career Development awards to scientists which the NWRCE has been administering during the initial award period, and Group Career Development and Training. The latter will conduct a continuing medical education (CME) course to educate primary care providers in Region X regarding the recognition and management of biodefense-related infections -- both from the individual case management and public health perspective. Our overall goal will be to develop and enhance an active and knowledgeable professional cadre to respond to infectious disease emergencies. The CME course will be undertaken in collaboration with Emergency Response Director Jeffery Duchin MD and the Puget Sound Seattle King County Health Department as a joint effort of both the Emergency Response Plan and the Group Career Development Plan.

Public Health Relevance

The Career Development and Training Program of the NWRCE is intended to 1) increase the number and quality of basic and clinical researchers working in biodefense and emerging infectious disease in Region X (WA, OR, AK, ID), and 2) enhance public health responsiveness in the event of an infectious disease emergency.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54AI057141-08
Application #
8236995
Study Section
Special Emphasis Panel (ZAI1)
Project Start
2011-03-01
Project End
2014-02-28
Budget Start
2011-03-01
Budget End
2012-02-29
Support Year
8
Fiscal Year
2011
Total Cost
$338,252
Indirect Cost
Name
University of Washington
Department
Type
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195
Hagar, Jon A; Edin, Matthew L; Lih, Fred B et al. (2017) Lipopolysaccharide Potentiates Insulin-Driven Hypoglycemic Shock. J Immunol 199:3634-3643
Hajjar, Adeline M; Ernst, Robert K; Yi, Jaehun et al. (2017) Expression level of human TLR4 rather than sequence is the key determinant of LPS responsiveness. PLoS One 12:e0186308
Jorgensen, Ine; Lopez, Joseph P; Laufer, Stefan A et al. (2016) IL-1?, IL-18, and eicosanoids promote neutrophil recruitment to pore-induced intracellular traps following pyroptosis. Eur J Immunol 46:2761-2766
Miller, Samuel I; Chaudhary, Anu (2016) A Cellular GWAS Approach to Define Human Variation in Cellular Pathways Important to Inflammation. Pathogens 5:
Fan, Vincent S; Gharib, Sina A; Martin, Thomas R et al. (2016) COPD disease severity and innate immune response to pathogen-associated molecular patterns. Int J Chron Obstruct Pulmon Dis 11:467-77
Jorgensen, Ine; Zhang, Yue; Krantz, Bryan A et al. (2016) Pyroptosis triggers pore-induced intracellular traps (PITs) that capture bacteria and lead to their clearance by efferocytosis. J Exp Med 213:2113-28
Hayden, Hillary S; Matamouros, Susana; Hager, Kyle R et al. (2016) Genomic Analysis of Salmonella enterica Serovar Typhimurium Characterizes Strain Diversity for Recent U.S. Salmonellosis Cases and Identifies Mutations Linked to Loss of Fitness under Nitrosative and Oxidative Stress. MBio 7:e00154
Chaudhary, Anu; Leite, Mara; Kulasekara, Bridget R et al. (2016) Human Diversity in a Cell Surface Receptor that Inhibits Autophagy. Curr Biol 26:1791-801
Majerczyk, Charlotte; Schneider, Emily; Greenberg, E Peter (2016) Quorum sensing control of Type VI secretion factors restricts the proliferation of quorum-sensing mutants. Elife 5:
Yen, Gloria S; Edgar, J Scott; Yoon, Sung Hwan et al. (2016) Polydimethylsiloxane microchannel coupled to surface acoustic wave nebulization mass spectrometry. Rapid Commun Mass Spectrom 30:1096-100

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