The Developmental Program, directed by Developmental Director Water Stamm MD of the Administrative Core consists of the Developmental Research Project Awards, described here, and the Career Development (individual and group activities) awards. Developmental Projects are established in order to expand the scope and excellence of biodefense and emerging infectious disease research ongoing within the NWRCE region (WA, OR, AK, ID) and to insure flexibility in the face of changing needs or priorities. Proposals are solicited, and awards are made to meritorious applicants that propose unique and promising research avenues that are underrepresented in the NWRCE or that expand or synergize with ongoing research projects. The NWRCE will make awards yearly on or about March 1. This arrangement will allow the Center to issue yearly RFAs for these (typically two year) projects, allowing the Center to be responsive to new opportunities and overall research directions. The ultimate aim of this program is to advance projects to a level at which other funding mechanisms can support the work.

Public Health Relevance

The Northwest Regional Center of Excellence for Biodefense and Emerging Infectious Diseases (NWRCE) sponsors a Developmental Research program which makes awards of 1 or 2 years of support for scientific research projects on pathogens of national interest. This mechanism is intended to increase the number, quality, and type of infectious disease research projects in DHHS Region X (WA, OR, AK, ID).

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54AI057141-10
Application #
8447100
Study Section
Special Emphasis Panel (ZAI1-DDS-M)
Project Start
Project End
2015-02-28
Budget Start
2013-03-01
Budget End
2014-02-28
Support Year
10
Fiscal Year
2013
Total Cost
$196,083
Indirect Cost
$61,777
Name
University of Washington
Department
Type
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195
Majerczyk, Charlotte; Schneider, Emily; Greenberg, E Peter (2016) Quorum sensing control of Type VI secretion factors restricts the proliferation of quorum-sensing mutants. Elife 5:
Miller, Samuel I; Chaudhary, Anu (2016) A Cellular GWAS Approach to Define Human Variation in Cellular Pathways Important to Inflammation. Pathogens 5:
Jorgensen, Ine; Zhang, Yue; Krantz, Bryan A et al. (2016) Pyroptosis triggers pore-induced intracellular traps (PITs) that capture bacteria and lead to their clearance by efferocytosis. J Exp Med 213:2113-28
Jorgensen, Ine; Lopez, Joseph P; Laufer, Stefan A et al. (2016) IL-1β, IL-18, and eicosanoids promote neutrophil recruitment to pore-induced intracellular traps following pyroptosis. Eur J Immunol 46:2761-2766
Chapman, John D; Edgar, J Scott; Goodlett, David R et al. (2016) Use of captive spray ionization to increase throughput of the data-independent acquisition technique PAcIFIC. Rapid Commun Mass Spectrom 30:1101-7
Hayden, Hillary S; Matamouros, Susana; Hager, Kyle R et al. (2016) Genomic Analysis of Salmonella enterica Serovar Typhimurium Characterizes Strain Diversity for Recent U.S. Salmonellosis Cases and Identifies Mutations Linked to Loss of Fitness under Nitrosative and Oxidative Stress. MBio 7:e00154
Fan, Vincent S; Gharib, Sina A; Martin, Thomas R et al. (2016) COPD disease severity and innate immune response to pathogen-associated molecular patterns. Int J Chron Obstruct Pulmon Dis 11:467-77
Yen, Gloria S; Edgar, J Scott; Yoon, Sung Hwan et al. (2016) Polydimethylsiloxane microchannel coupled to surface acoustic wave nebulization mass spectrometry. Rapid Commun Mass Spectrom 30:1096-100
Salipante, Stephen J; Roach, David J; Kitzman, Jacob O et al. (2015) Large-scale genomic sequencing of extraintestinal pathogenic Escherichia coli strains. Genome Res 25:119-28
Maltez, Vivien I; Tubbs, Alan L; Cook, Kevin D et al. (2015) Inflammasomes Coordinate Pyroptosis and Natural Killer Cell Cytotoxicity to Clear Infection by a Ubiquitous Environmental Bacterium. Immunity 43:987-97

Showing the most recent 10 out of 240 publications