The purpose of the WRCE career development plan is to offer research and research support training opportunities, including individual Career Development projects and group Career Development activities. The individual Career Development Program will target junior faculty who wish to pursue a career in infectious diseases research. The overall goals will be to increase and strengthen the trainee's research skills and knowledge through a carefully mentored, individually tailored research program and research support activities. Multidisciplinary mentorship of career development trainees will be provided to ensure that research activities are adequately focused, and to provide assistance for the transition from basic discovery to product development, and eventually clinical evaluation. The overall goals of the Group Career Development program will be to increase and strengthen the trainee's knowledge and technical skills to support biodefense and emerging infectious diseases research. This program is intended to provide multidisciplinary opportunities for trainees, to ensure that the group activities are adequately focused, and to assist the transition from basic discovery to product development and clinical evaluation. In the initial grant year, group Career Development activities will be organized as a biosafety containment laboratory training program that will be designed to provide training opportunities to biodefense and emerging infectious disease researchers, including faculty, postdoctoral fellows, graduate students, and technicians to learn how to safely conduct research in biosafety level 2, 3, and/or 4 laboratories. A systematic and rigorous administrative and scientific management plan will be employed to allow for the selection of the most relevant and scientifically sound proposals, and for effectively monitoring and evaluating the program. The WRCE Director will have overall responsibility for the group Career Development activities and will designate the WRCE Associate Director to manage the plan. The Associate Director will be supported by the WRCE Program Administrator and other key WRCE Administrative Core personnel. All group career development projects will be evaluated for usage and value to the WRCE program. In addition, the plan will insure that the solicitation of project proposals is open and announced publicly, and that a special effort is made to recruit women and minorities.

Public Health Relevance

The WRCE individual Career Development program will contribute to training the next generation of scientists to become independent researchers, so that they may productively investigate biodefense and emerging infectious disease agents. The group Career Development program will train researchers, students, and technicians to understand and apply specific theoretical and practical biomedical research skills, such as the capability to safely perform research in biocontainment laboratories.

National Institute of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Specialized Center--Cooperative Agreements (U54)
Project #
Application #
Study Section
Special Emphasis Panel (ZAI1-DDS-M)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Texas Medical Br Galveston
United States
Zip Code
Pandey, Aseem; Lin, Furong; Cabello, Ana L et al. (2018) Activation of Host IRE1?-Dependent Signaling Axis Contributes the Intracellular Parasitism of Brucella melitensis. Front Cell Infect Microbiol 8:103
Russell-Lodrigue, Kasi E; Killeen, Stephanie Z; Ficht, Thomas A et al. (2018) Mucosal bacterial dissemination in a rhesus macaque model of experimental brucellosis. J Med Primatol 47:75-77
Matz, L M; Kamdar, K Y; Holder, M E et al. (2018) Challenges of Francisella classification exemplified by an atypical clinical isolate. Diagn Microbiol Infect Dis 90:241-247
Langsjoen, Rose M; Haller, Sherry L; Roy, Chad J et al. (2018) Chikungunya Virus Strains Show Lineage-Specific Variations in Virulence and Cross-Protective Ability in Murine and Nonhuman Primate Models. MBio 9:
Raja, B; Goux, H J; Marapadaga, A et al. (2017) Development of a panel of recombinase polymerase amplification assays for detection of common bacterial urinary tract infection pathogens. J Appl Microbiol 123:544-555
Nunes, Marcio R T; Contreras-Gutierrez, María Angélica; Guzman, Hilda et al. (2017) Genetic characterization, molecular epidemiology, and phylogenetic relationships of insect-specific viruses in the taxon Negevirus. Virology 504:152-167
Rossetti, Carlos A; Drake, Kenneth L; Lawhon, Sara D et al. (2017) Systems Biology Analysis of Temporal In vivo Brucella melitensis and Bovine Transcriptomes Predicts host:Pathogen Protein-Protein Interactions. Front Microbiol 8:1275
Paterson, Andrew S; Raja, Balakrishnan; Mandadi, Vinay et al. (2017) A low-cost smartphone-based platform for highly sensitive point-of-care testing with persistent luminescent phosphors. Lab Chip 17:1051-1059
Park, Arnold; Yun, Tatyana; Vigant, Frederic et al. (2016) Nipah Virus C Protein Recruits Tsg101 to Promote the Efficient Release of Virus in an ESCRT-Dependent Pathway. PLoS Pathog 12:e1005659
Pandey, Aseem; Cabello, Ana; Akoolo, Lavoisier et al. (2016) The Case for Live Attenuated Vaccines against the Neglected Zoonotic Diseases Brucellosis and Bovine Tuberculosis. PLoS Negl Trop Dis 10:e0004572

Showing the most recent 10 out of 384 publications