The Northeast Biodefense Center is a Regional Center of Excellence for Research in Biodefense and Emerging Infectious Diseases that represents more than 350 investigators in more than 30 institutions in New York, New Jersey, Connecticut, Puerto Rico and the Virgin Islands. The mission of Administrative Core is to promote research and training programs in biodefense by distributing awards for research and career development, supporting core facilities, and facilitating communication and collaboration through meetings and electronic media. The Core has three sites, one at Columbia University, where the Director and Principal Investigator (Lipkin), and Associate Director (Diane McFadden) coordinate scientific, fiscal and communicative aspects of the program, a second site at the Wadsworth Center of the New York State Department of Health, where the Wadsworth Center Liaison (Harry Taber) and Public Health Liaison (Lawrence Sturman) coordinate the Developmental Projects and Career Development Programs as well as Emergency Response Planning, and a third at the Albert Einstein College of Medicine where the Deputy Director (Arturo Casadevall) works closely with the Director in coordinating the Center and monitors the Animal, Expression and Proteomics cores. The Administrative Core reports to a Steering Committee comprised of representatives from the lead institutions: the Albert Einstein College of Medicine, Columbia University, Cornell University, Mt. Sinai School of Medicine, New York University, The Rockefeller University, SUNY Stony Brook, University of Medicine and Dentistry of New Jersey, Wadsworth Center and Yale University. The Administrative Core pursues an annual review of NBC performance considering such metrics as publications, inventions, meetings and training course offered and attended, scientists recruited and/or trained in biodefense research, intra- and inter-RCE collaborations fostered, and Scientific Advisory Board and NBC member evalutions. Every two years, in consultation with NIAID program staff, the Core engages an outside entity for a formal independent assessment of center performance.

National Institute of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Specialized Center--Cooperative Agreements (U54)
Project #
Application #
Study Section
Special Emphasis Panel (ZAI1-DDS-M)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Columbia University (N.Y.)
New York
United States
Zip Code
Charles, Jermilia; Firth, Andrew E; Loroño-Pino, Maria A et al. (2016) Merida virus, a putative novel rhabdovirus discovered in Culex and Ochlerotatus spp. mosquitoes in the Yucatan Peninsula of Mexico. J Gen Virol 97:977-87
Pham, Alissa M; Santa Maria, Felicia Gilfoy; Lahiri, Tanaya et al. (2016) PKR Transduces MDA5-Dependent Signals for Type I IFN Induction. PLoS Pathog 12:e1005489
Song, Jeongmin; Wilhelm, Cara L; Wangdi, Tamding et al. (2016) Absence of TLR11 in Mice Does Not Confer Susceptibility to Salmonella Typhi. Cell 164:827-8
Li, Melody M H; Bozzacco, Leonia; Hoffmann, Hans-Heinrich et al. (2016) Interferon regulatory factor 2 protects mice from lethal viral neuroinvasion. J Exp Med 213:2931-2947
Moser, Lindsey A; Lim, Pei-Yin; Styer, Linda M et al. (2016) Parameters of Mosquito-Enhanced West Nile Virus Infection. J Virol 90:292-9
Basu, Debaleena; Kahn, Jennifer N; Li, Xiao-Ping et al. (2016) Conserved Arginines at the P-Protein Stalk Binding Site and the Active Site Are Critical for Ribosome Interactions of Shiga Toxins but Do Not Contribute to Differences in the Affinity of the A1 Subunits for the Ribosome. Infect Immun 84:3290-3301
Steyer, Andrej; Jevšnik, Monika; Petrovec, Miroslav et al. (2016) Narrowing of the Diagnostic Gap of Acute Gastroenteritis in Children 0-6 Years of Age Using a Combination of Classical and Molecular Techniques, Delivers Challenges in Syndromic Approach Diagnostics. Pediatr Infect Dis J 35:e262-70
Uhde, Melanie; Ajamian, Mary; Li, Xueting et al. (2016) Expression of C-Reactive Protein and Serum Amyloid A in Early to Late Manifestations of Lyme Disease. Clin Infect Dis 63:1399-1404
Jacek, Elzbieta; Tang, Kevin S; Komorowski, Lars et al. (2016) Epitope-Specific Evolution of Human B Cell Responses to Borrelia burgdorferi VlsE Protein from Early to Late Stages of Lyme Disease. J Immunol 196:1036-43
Aguilar, Jorge L; Varshney, Avanish K; Pechuan, Ximo et al. (2016) Monoclonal antibodies protect from Staphylococcal Enterotoxin K (SEK) induced toxic shock and sepsis by USA300 Staphylococcus aureus. Virulence :1-10

Showing the most recent 10 out of 643 publications